Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.33 |
| ▸ | PIK3R2 | O00459 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.33 |
| ▸ | PIK3R5 | Q8WYR1 | 2/20 | 0.33 |
| ▸ | PIK3R3 | Q92569 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834320 | 0.90 | PIK3CD (0.39) | MAPTPOLBPIK3CDPIK3R2PIK3CA | |
| SCHEMBL9831843 | 0.89 | MAPK13 (0.37) | MAPTMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL9833627 | 0.88 | PIK3CD (0.45) | MAPTPOLBPIK3CDPIK3R2PIK3CA | |
| SCHEMBL9831070 | 0.88 | NR1H4 (0.41) | MAPTPOLBALDH1A1LMNACCNA2 | |
| SCHEMBL9834220 | 0.88 | NR1H4 (0.40) | MAPTPOLBPIK3CDPIK3R2PIK3CA | |
| SCHEMBL9833961 | 0.88 | PIK3CD (0.40) | MAPTPOLBPIK3CDPIK3R2PIK3CA | |
| SCHEMBL9316299 | 0.88 | MAPT (0.39) | MAPTPOLBPIK3CDPIK3R2PIK3CA | |
| SCHEMBL9316748 | 0.87 | MAPT (0.44) | MAPTPOLBPIK3CDPIK3R2PIK3CA | |
| SCHEMBL9833919 | 0.87 | PIK3CD (0.41) | MAPTPOLBMAPK13MAPK12MAPK11 | |
| SCHEMBL9522469 | 0.87 | PIK3CD (0.36) | MAPTPOLBPIK3CDPIK3R2PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4816467-A | BACTERICIDES, VIRICIDES | FARMITALIA CARLO ERBA S.R.L (IT) | 1989-03-28 | — | — | US | disclosed |
| EP-0274443-A1 | Heteroaryl 3-oxo-propanenitrile derivatives and process for their preparation | FARMITALIA CARLO ERBA S.r.l. (IT) | 1988-07-13 | — | — | EP | disclosed |