Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA1 | P02708 | 1/20 | 0.67 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.67 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9839034 | 0.95 | SMN1; SMN2 (0.65) | CHRNA1CHRNA3CHRNA7SMN1; SMN2ALDH1A1 | |
| SCHEMBL9839038 | 0.95 | SMN1; SMN2 (0.65) | CHRNA1CHRNA3CHRNA7SMN1; SMN2ALDH1A1 | |
| SCHEMBL9839937 | 0.89 | CHRNA1 (0.68) | CHRNA1CHRNA3CHRNA7SMN1; SMN2ALDH1A1 | |
| SCHEMBL9070364 | 0.86 | CHRNA1 (0.72) | CHRNA1CHRNA3CHRNA7SMN1; SMN2ALDH1A1 | |
| SCHEMBL9840527 | 0.84 | SMN1; SMN2 (0.66) | CHRNA1CHRNA3CHRNA7SMN1; SMN2ALDH1A1 | |
| SCHEMBL10565107 | 0.84 | SMN1; SMN2 (0.66) | CHRNA1CHRNA3CHRNA7SMN1; SMN2ALDH1A1 | |
| SCHEMBL10568148 | 0.82 | CHRNB2 (0.46) | CHRNA1CHRNA3CHRNA7SMN1; SMN2ALDH1A1 | |
| SCHEMBL9070419 | 0.82 | CHRNA1 (0.76) | CHRNA1CHRNA3CHRNA7SMN1; SMN2ALDH1A1 | |
| SCHEMBL9391228 | 0.81 | SMN1; SMN2 (0.69) | CHRNA1CHRNA3CHRNA7SMN1; SMN2ALDH1A1 | |
| SCHEMBL9391231 | 0.81 | SMN1; SMN2 (0.69) | CHRNA1CHRNA3CHRNA7SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4812454-A | Nitromethylene derivatives and their use as insecticides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-03-14 | — | — | US | claimed |
| US-4772620-A | MITICIDES, PARASITICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1988-09-20 | — | — | US | claimed |