Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 2/20 | 0.41 |
| ▸ | CASP6 | P55212 | 2/20 | 0.41 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.41 |
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | CASP9 | P55211 | 1/20 | 0.33 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14917574 | 0.76 | ADRA2A (0.33) | SMN1; SMN2ADRA2AADRA2BADRA2C | |
| SCHEMBL25266 | 0.76 | — | — | |
| Succinimide SCHEMBL10568470 | 0.76 | CRBN (0.39) | PARP1LMNA | |
| Propane SCHEMBL28148423 | 0.74 | ADRA2A (0.32) | SMN1; SMN2ADRA2AADRA2BADRA2C | |
| Ammonia Solution, Strong SCHEMBL27742777 | 0.74 | ADRA2A (0.32) | SMN1; SMN2ADRA2AADRA2BADRA2C | |
| SCHEMBL3919995 | 0.74 | ADRA2A (0.32) | SMN1; SMN2ADRA2AADRA2BADRA2C | |
| SCHEMBL6683456 | 0.74 | — | — | |
| Oxirane SCHEMBL28312924 | 0.72 | ADRA2A (0.34) | ADRA2AADRA2BADRA2C | |
| SCHEMBL9113436 | 0.72 | SMN1; SMN2 (0.43) | SMN1; SMN2ADRA2AADRA2BADRA2CLMNA | |
| Phthalimide SCHEMBL28193801 | 0.72 | GSK3B (0.79) | GSK3BCASP3CASP7CASP6CASP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4831161-A | CHEMICAL INTERMEDIATES | THE DOW CHEMICAL COMPANY (US) | 1989-05-16 | — | — | US | disclosed |
| US-4692533-A | IMIDE, 2-OXAZOLINE | THE DOW CHEMICAL COMPANY (US) | 1987-09-08 | — | — | US | disclosed |