Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | AGXT | P21549 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3713270 | 0.94 | TSHR (0.43) | TSHRIDO1TP53AGXTALDH1A1 | |
| SCHEMBL5411417 | 0.90 | TSHR (0.43) | TSHRIDO1TP53AGXTALDH1A1 | |
| SCHEMBL9155752 | 0.84 | CETP (0.42) | TSHRIDO1TP53AGXTALDH1A1 | |
| SCHEMBL18297917 | 0.82 | TSHR (0.48) | TSHRIDO1TP53AGXTALDH1A1 | |
| SCHEMBL18297912 | 0.82 | TSHR (0.48) | TSHRIDO1TP53AGXTALDH1A1 | |
| SCHEMBL18297913 | 0.80 | TSHR (0.46) | TSHRIDO1TP53AGXTALDH1A1 | |
| SCHEMBL28012339 | 0.80 | TSHR (0.46) | TSHRIDO1TP53AGXTALDH1A1 | |
| SCHEMBL28136105 | 0.79 | CETP (0.40) | TSHRIDO1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL11418600 | 0.78 | TSHR (0.44) | TSHRIDO1TP53AGXTALDH1A1 | |
| SCHEMBL8561019 | 0.78 | TSHR (0.40) | TSHRIDO1TP53AGXTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3103805-B1 | SILANOL COMPOUND, COMPOSITION, AND METHOD FOR PRODUCING SILANOL COMPOUND | AIST (JP) | 2020-11-18 | — | — | EP | disclosed |
| US-10308670-B2 | Silanol compound, composition, and method for producing silanol compound | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2019-06-04 | — | — | US | disclosed |
| US-20170183363-A1 | Silanol Compound, Composition, and Method for Producing Silanol Compound | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2017-06-29 | — | — | US | disclosed |
| EP-3103805-A1 | SILANOL COMPOUND, COMPOSITION, AND METHOD FOR PRODUCING SILANOL COMPOUND | National Institute of Advanced Industrial Science and Technology (JP) | 2016-12-14 | — | — | EP | disclosed |
| US-4831091-A | USING A COORDINATION CATALYST CONTAINING A SILANETRIOL OR -DIOL AS WELL AS AN AROMATIC ESTSER; ODORLESS; STEREOSPECIFIC; PARTICLE SIZES | CHISSO CORPORATION (JP) | 1989-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170183363-A1 | Silanol Compound, Composition, and Method for Producing Silanol Compound | LSS, MSMO1, ALG3 | TSHR 4865/4885IDO1 3463/4885TP53 2082/4885 |
| US-10308670-B2 | Silanol compound, composition, and method for producing silanol compound | LSS, MSMO1, ALG3 | TSHR 4865/4885IDO1 3463/4885TP53 2082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.