SCHEMBL9155752

SCHEMBL9155752

CCCC[Si](OCc1ccccc1)(OCc1ccccc1)OCc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CETP P11597 3/20 0.42
TSHR P16473 2/20 0.41
ALDH1A1 P00352 1/20 0.41
CYP3A4 P08684 1/20 0.41
MAPK1 P28482 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
IDO1 P14902 1/20 0.39
TP53 P04637 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
SIGMAR1 Q99720 1/20 0.38
TLR8 Q9NR97 1/20 0.38
TLR7 Q9NYK1 1/20 0.38
AGXT P21549 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28136105 0.91 CETP (0.40) CETPTSHRALDH1A1CYP3A4MAPK1
SCHEMBL10568248 0.84 TSHR (0.48) TSHRALDH1A1MAPK1TDP1L3MBTL1
SCHEMBL729820 0.81 TSHR (0.35) CETPTSHRALDH1A1MAPK1TDP1
SCHEMBL11600226 0.81 MAOA (0.45) TSHRL3MBTL1IDO1SMN1; SMN2AGXT
SCHEMBL26661022 0.81 TSHR (0.41) TSHRALDH1A1MAPK1TDP1L3MBTL1
SCHEMBL11419784 0.81 TSHR (0.41) TSHRALDH1A1IDO1AGXT
SCHEMBL10713783 0.81 TSHR (0.41) TSHRALDH1A1MAPK1TDP1L3MBTL1
SCHEMBL27614173 0.80 CETP (0.40) CETPTSHRALDH1A1CYP3A4MAPK1
SCHEMBL28478011 0.80 CETP (0.40) CETPMAPK1TP53SMN1; SMN2
SCHEMBL17697645 0.79 CETP (0.45) CETPTSHRALDH1A1CYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0401540-B1 Process for crosslinking hydrolyzable copolymers UNION CARBIDE CHEM PLASTIC (US) 1995-03-01 EP disclosed
US-5047476-A Mixing copolymer containing hydrolyzable grafted silicon group dihydrocarbyltin oxide, carboxylic acid, water, then heating UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) 1991-09-10 US disclosed
EP-0401540-A2 Process for crosslinking hydrolyzable copolymers UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) 1990-12-12 EP disclosed