Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 6/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10482576 | 0.88 | HRH1 (0.51) | HRH1KCNH2HTTRECQLNPSR1 | |
| SCHEMBL10479170 | 0.84 | KCNH2 (0.47) | HRH1KCNH2HTTRECQLNPSR1 | |
| SCHEMBL10568072 | 0.80 | HRH1 (0.62) | HRH1KCNH2 | |
| SCHEMBL10479193 | 0.80 | NPC1 (0.51) | HRH1KCNH2HTTRECQLNPSR1 | |
| SCHEMBL3317162 | 0.78 | HRH1 (0.48) | HRH1KCNH2 | |
| SCHEMBL10568040 | 0.77 | HRH1 (0.56) | HRH1KCNH2MEN1 | |
| SCHEMBL16291199 | 0.76 | KCNH2 (0.67) | HRH1KCNH2HTTNPSR1MEN1 | |
| SCHEMBL55533 | 0.76 | HRH1 (0.67) | HRH1KCNH2 | |
| SCHEMBL10479209 | 0.76 | HRH1 (0.63) | HRH1KCNH2 | |
| SCHEMBL9786914 | 0.74 | HRH1 (0.66) | HRH1KCNH2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4853387-A | Piperidine derivatives, and their application in therapy | SYNTHELABO (FR) | 1989-08-01 | — | — | US | disclosed |