Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 5/20 | 0.62 |
| ▸ | CARM1 | Q86X55 | 4/20 | 0.58 |
| ▸ | PRMT6 | Q96LA8 | 4/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10569296 | 0.86 | CARM1 (0.54) | HRH1CARM1PRMT6KCNH2 | |
| SCHEMBL55533 | 0.84 | HRH1 (0.67) | HRH1KCNH2 | |
| SCHEMBL9874299 | 0.81 | HTT (0.60) | HRH1KCNH2 | |
| SCHEMBL10479209 | 0.81 | HRH1 (0.63) | HRH1KCNH2 | |
| SCHEMBL14020878 | 0.80 | HRH1 (0.65) | HRH1KCNH2 | |
| SCHEMBL10568293 | 0.80 | HRH1 (0.53) | HRH1KCNH2 | |
| SCHEMBL9786914 | 0.79 | HRH1 (0.66) | HRH1KCNH2 | |
| SCHEMBL9872567 | 0.79 | CYP2J2 (0.67) | HRH1KCNH2 | |
| SCHEMBL14573205 | 0.79 | CYP2J2 (0.62) | HRH1KCNH2 | |
| SCHEMBL5694766 | 0.78 | HRH1 (0.68) | HRH1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4853387-A | Piperidine derivatives, and their application in therapy | SYNTHELABO (FR) | 1989-08-01 | — | — | US | disclosed |