Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27983586 | 0.86 | CYP3A4 (0.44) | MAPTTSHRHSD17B10CYP3A4TDP1 | |
| SCHEMBL14313835 | 0.82 | MAPT (0.50) | MAPTTSHRHSD17B10CYP3A4TDP1 | |
| SCHEMBL9468840 | 0.82 | TSHR (0.44) | MAPTTSHRHSD17B10CYP3A4TDP1 | |
| SCHEMBL28584328 | 0.80 | MAPT (0.48) | MAPTTSHRHSD17B10CYP3A4TDP1 | |
| SCHEMBL28781548 | 0.80 | CA12 (0.56) | MAPTHSD17B10L3MBTL1ALOX15MEN1 | |
| SCHEMBL9468884 | 0.79 | CA12 (0.46) | MAPTTSHRHSD17B10CYP3A4TDP1 | |
| Hydrochloric Acid SCHEMBL28703929 | 0.79 | CA12 (0.54) | MAPTHSD17B10L3MBTL1ALOX15MEN1 | |
| SCHEMBL8526926 | 0.79 | MAPT (0.52) | MAPTTSHRHSD17B10CYP3A4TDP1 | |
| SCHEMBL27552924 | 0.77 | CES1 (0.52) | MAPTTSHRHSD17B10CYP3A4TDP1 | |
| SCHEMBL4163523 | 0.77 | MMP12 (0.50) | MAPTTSHRHSD17B10CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4831161-A | CHEMICAL INTERMEDIATES | THE DOW CHEMICAL COMPANY (US) | 1989-05-16 | — | — | US | disclosed |
| US-4692533-A | IMIDE, 2-OXAZOLINE | THE DOW CHEMICAL COMPANY (US) | 1987-09-08 | — | — | US | disclosed |
| US-4259499-A | Method for preparing 2-sulfochloride benzoates and the use of same in the preparation of saccharin | JAMES RIVER GRAPHICS INC. (US) | 1981-03-31 | — | — | US | disclosed |
| US-4042600-A | Pyrolysis of 2-sulfochloride benzoates | SCOTT PAPER COMPANY (US) | 1977-08-16 | — | — | US | disclosed |