Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 11/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 10/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10567394 | 0.88 | MAPK14 (0.54) | MAPK14PTGS1PTGS2 | |
| SCHEMBL10567547 | 0.78 | PTGS2 (0.52) | MAPK14PTGS1PTGS2 | |
| SCHEMBL6050629 | 0.78 | PTGS2 (0.49) | MAPK14PTGS1PTGS2 | |
| SCHEMBL10843937 | 0.75 | MAPK14 (0.79) | MAPK14PTGS1PTGS2 | |
| SCHEMBL10954902 | 0.73 | MAPK14 (0.51) | MAPK14PTGS1PTGS2 | |
| SCHEMBL10909626 | 0.73 | PTGS2 (0.39) | MAPK14PTGS1PTGS2 | |
| SCHEMBL6050640 | 0.72 | PTGS2 (0.52) | MAPK14PTGS1PTGS2 | |
| SCHEMBL7833395 | 0.72 | PTGS2 (0.52) | MAPK14PTGS1PTGS2 | |
| SCHEMBL14922922 | 0.71 | NISCH (0.39) | — | |
| SCHEMBL18516555 | 0.71 | ESR1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4820827-A | 2,3-diaryl-5-bromothiophene compounds of use for the treatment of inflammaton and dysmenorrhea | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-04-11 | — | — | US | disclosed |