Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 16/20 | 0.77 |
| ▸ | MAOB | P27338 | 16/20 | 0.77 |
| ▸ | DRD2 | P14416 | 3/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10573572 | 0.94 | MAOA (0.79) | MAOAMAOBDRD2 | |
| SCHEMBL29487495 | 0.88 | MAOB (0.70) | MAOAMAOBDRD2 | |
| SCHEMBL18825568 | 0.88 | MAOB (0.70) | MAOAMAOBDRD2 | |
| SCHEMBL10571208 | 0.87 | MAOA (0.79) | MAOAMAOBDRD2 | |
| SCHEMBL25570556 | 0.86 | MAOA (0.83) | MAOAMAOBDRD2 | |
| SCHEMBL16559664 | 0.86 | MAOA (1.00) | MAOAMAOBDRD2 | |
| SCHEMBL10571777 | 0.86 | MAOA (0.74) | MAOAMAOBDRD2 | |
| SCHEMBL10572893 | 0.86 | MAOA (0.72) | MAOAMAOBDRD2 | |
| SCHEMBL8264157 | 0.85 | MAOA (0.81) | MAOAMAOBDRD2 | |
| SCHEMBL10570502 | 0.85 | MAOA (0.83) | MAOAMAOBDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4824840-A | ANTIHISTAMINES, NERVOUS SYSTEM CONTROLLERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-25 | — | — | US | disclosed |
| US-4734416-A | ANTIHISTAMINES, CENTRAL NERVOUS SYSTEM CONTROLLING ACTION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-29 | — | — | US | disclosed |