Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10570522 | 1.00 | CYP3A4 (0.39) | CYP3A4TDP1ESR1ESR2TNFRSF1A | |
| SCHEMBL10576170 | 0.90 | — | — | |
| SCHEMBL19019980 | 0.81 | TNFRSF1A (0.46) | CYP3A4TDP1ESR1ESR2TNFRSF1A | |
| SCHEMBL6908077 | 0.81 | DRD1 (0.33) | CYP3A4 | |
| SCHEMBL10655732 | 0.75 | TNFRSF1A (0.32) | TNFRSF1A | |
| SCHEMBL10567856 | 0.74 | CA2 (0.48) | CYP3A4TDP1ESR1ESR2TNFRSF1A | |
| SCHEMBL10567591 | 0.74 | CA2 (0.48) | CYP3A4TDP1ESR1ESR2TNFRSF1A | |
| SCHEMBL12488383 | 0.73 | CA2 (0.44) | TDP1KDM4E | |
| SCHEMBL1826724 | 0.70 | PTGDR2 (0.33) | KDM4E | |
| SCHEMBL9637933 | 0.70 | MAPT (0.36) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4835202-A | (Hydroxyphenyl) phosphine stabilized compositions | CIBA-GEIGY CORPORATION (US) | 1989-05-30 | — | — | US | claimed |
| US-4835202-A | (Hydroxyphenyl) phosphine stabilized compositions | CIBA-GEIGY CORPORATION (US) | 1989-05-30 | — | — | US | disclosed |