Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | NMT2 | O60551 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.48 |
| ▸ | NMT1 | P30419 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10569167 | 0.95 | LMNA (0.62) | LMNAALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL14176537 | 0.82 | GAA (0.50) | LMNAALDH1A1SMN1; SMN2KDM4EGAA | |
| SCHEMBL16676720 | 0.81 | LMNA (0.68) | LMNAALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL8154526 | 0.78 | LMNA (0.74) | LMNAALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL10460344 | 0.78 | LMNA (0.72) | LMNAALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL26724557 | 0.78 | LMNA (0.62) | LMNAALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL14176499 | 0.77 | GAA (0.55) | LMNAALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL2560414 | 0.77 | LMNA (0.60) | LMNAALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL13313222 | 0.76 | LMNA (0.73) | LMNAALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL524256 | 0.76 | LMNA (0.73) | LMNAALDH1A1SMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4853408-A | 4-phenylpropyl-indoles having antiarythmic activity | ROUSSEL UCLAF (FR) | 1989-08-01 | — | — | US | disclosed |