Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10570255 | 0.89 | MEN1 (0.52) | MEN1KMT2AHTR7ALDH1A1SLC6A2 | |
| SCHEMBL10568967 | 0.88 | MEN1 (0.45) | MEN1KMT2AHTR7ALDH1A1SLC6A2 | |
| SCHEMBL10570196 | 0.86 | MAPT (0.44) | MEN1KMT2AALDH1A1SLC6A2L3MBTL1 | |
| SCHEMBL10570669 | 0.86 | MEN1 (0.54) | MEN1KMT2AALDH1A1TP53HPGD | |
| SCHEMBL10571141 | 0.84 | MEN1 (0.48) | MEN1KMT2AALDH1A1SLC6A2P2RX7 | |
| SCHEMBL10567819 | 0.84 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1SLC6A2TP53 | |
| SCHEMBL10575996 | 0.83 | TSHR (0.52) | MEN1KMT2AHTR7ALDH1A1TP53 | |
| SCHEMBL10565747 | 0.81 | MEN1 (0.48) | MEN1KMT2AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL10570315 | 0.79 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL10571542 | 0.79 | MEN1 (0.53) | MEN1KMT2AHTR7ALDH1A1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4847285-A | 1-substituted phenyl-3-substituted methyl-pyrrolidine-2,5-diones and plant fungicide compositions containing same | THE DOW CHEMICAL COMPANY (US) | 1989-07-11 | — | — | US | disclosed |
| EP-0173284-A1 | Substituted 1-phenyl-3-methyl-pyrrolidindiones, their manufacture and use as fungicides | THE DOW CHEMICAL COMPANY (US) | 1986-03-05 | — | — | EP | disclosed |