Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.63 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.63 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.63 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.63 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.62 |
| ▸ | IGF1R | P08069 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL581719 | 1.00 | CASP3 (0.63) | CASP3SENP8SENP7SENP6CALM1 | |
| SCHEMBL3220290 | 0.98 | CASP3 (0.61) | CASP3SENP8SENP7SENP6CALM1 | |
| SCHEMBL10571533 | 0.98 | CASP3 (0.61) | CASP3SENP8SENP7SENP6CALM1 | |
| SCHEMBL4055705 | 0.98 | CASP3 (0.61) | CASP3SENP8SENP7SENP6CALM1 | |
| SCHEMBL3220040 | 0.98 | CASP3 (0.61) | CASP3SENP8SENP7SENP6CALM1 | |
| SCHEMBL10533113 | 0.98 | CASP3 (0.61) | CASP3SENP8SENP7SENP6CALM1 | |
| SCHEMBL10534584 | 0.98 | CASP3 (0.61) | CASP3SENP8SENP7SENP6CALM1 | |
| SCHEMBL2615719 | 0.98 | CASP3 (0.61) | CASP3SENP8SENP7SENP6CALM1 | |
| SCHEMBL28861182 | 0.98 | CASP3 (0.61) | CASP3SENP8SENP7SENP6CALM1 | |
| SCHEMBL10808884 | 0.98 | CASP3 (0.61) | CASP3SENP8SENP7SENP6CALM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4834905-A | LIQUID CRYSTAL DIELECTRICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-05-30 | — | — | US | disclosed |
| US-4627933-A | ESTERS, ETHERS, NITRICES, HALIDES, OR HYDROCARBONS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1986-12-09 | — | — | US | disclosed |
| EP-0104327-A2 | Use of cyclic derivatives as components of liquid cristals | MERCK PATENT GmbH (DE) | 1984-04-04 | — | — | EP | disclosed |