Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 7/20 | 0.72 |
| ▸ | EPHA2 | P29317 | 3/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.72 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.72 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.72 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.72 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.72 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.72 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.72 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.72 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.72 |
| ▸ | CASP7 | P55210 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14812914 | 0.96 | GPBAR1 (0.73) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL1011985 | 0.96 | GPBAR1 (0.73) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL1011986 | 0.96 | GPBAR1 (0.73) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL27276852 | 0.96 | GPBAR1 (0.73) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL19313992 | 0.96 | GPBAR1 (0.73) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| Sulfuric Acid SCHEMBL3905020 | 0.92 | GPBAR1 (0.71) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL7705524 | 0.91 | GPBAR1 (0.69) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL26753694 | 0.90 | GPBAR1 (0.75) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL7701568 | 0.90 | GPBAR1 (0.75) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL18689426 | 0.90 | GPBAR1 (0.75) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109831915-A | TLR 9-targeted spherical nucleic acid with strong anti-tumor activity | 埃克西奎雷股份有限公司 | 2019-05-31 | — | — | CN | claimed |
| CN-114942292-B | Method for detecting content of plant sterol substances in blood based on liquid chromatography-tandem mass spectrometry technology | 中国医学科学院阜外医院 | 2023-09-12 | — | — | CN | disclosed |
| CN-114942292-A | Method for detecting content of phytosterol substances in blood based on liquid chromatography-tandem mass spectrometry technology | 中国医学科学院阜外医院 | 2022-08-26 | — | — | CN | disclosed |
| CN-109831915-A | TLR 9-targeted spherical nucleic acid with strong anti-tumor activity | 埃克西奎雷股份有限公司 | 2019-05-31 | — | — | CN | disclosed |
| CN-206192957-U | Test system and preceding processing apparatus of sample of synthetic absorption marker thing of cholesterol | 杭州量康科技有限公司 | 2017-05-24 | — | — | CN | disclosed |
| CN-1728937-B | Time-specific seed promoters for expressing genes in plants | MONSANTO TECHNOLOGY LLC | 2011-03-30 | — | — | CN | disclosed |
| CN-101633924-A | Seed specific USP promoters for expressing genes in plants | MONSANTO TECHNOLOGY LLC | 2010-01-27 | — | — | CN | disclosed |
| CN-100543136-C | Seed-specific USP promoter for expressing genes in plants | MONSANTO TECHNOLOGY LLC (US) | 2009-09-23 | — | — | CN | disclosed |
| CN-1728937-A | Time-specific seed promoters for expressing genes in plants | MONSANTO TECHNOLOGY LLC (US) | 2006-02-01 | — | — | CN | disclosed |
| CN-1685040-A | Seed-specific USP promoter for expressing genes in plants | MONSANTO TECHNOLOGY LLC (US) | 2005-10-19 | — | — | CN | disclosed |
| EP-0331477-A2 | Organic dye thin film and organic thin film element | KABUSHIKI KAISHA TOSHIBA (JP) | 1989-09-06 | — | — | EP | disclosed |