Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 16/20 | 0.66 |
| ▸ | DRD3 | P35462 | 7/20 | 0.58 |
| ▸ | DRD4 | P21917 | 6/20 | 0.58 |
| ▸ | HTR1A | P08908 | 3/20 | 0.54 |
| ▸ | HTR7 | P34969 | 3/20 | 0.54 |
| ▸ | HTR6 | P50406 | 3/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10572205 | 0.91 | DRD2 (0.69) | DRD2DRD3DRD4HTR1AHTR7 | |
| SCHEMBL11303471 | 0.87 | DRD2 (0.55) | DRD2DRD3DRD4 | |
| SCHEMBL10662890 | 0.87 | DRD2 (0.62) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL10570148 | 0.85 | DRD2 (0.59) | DRD2DRD3DRD4HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL10569016 | 0.84 | DRD2 (0.58) | DRD2DRD3DRD4HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL10569951 | 0.84 | DRD2 (0.58) | DRD2DRD3DRD4HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL11406538 | 0.83 | DRD2 (0.50) | DRD2DRD3DRD4HTR1A | |
| SCHEMBL10838437 | 0.83 | DRD2 (0.55) | DRD2DRD3DRD4HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL10835643 | 0.82 | DRD2 (0.54) | DRD2DRD3DRD4HTR1AHTR7 | |
| SCHEMBL10573201 | 0.82 | DRD2 (0.95) | DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4734416-A | ANTIHISTAMINES, CENTRAL NERVOUS SYSTEM CONTROLLING ACTION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-29 | — | — | US | claimed |
| US-4824840-A | ANTIHISTAMINES, NERVOUS SYSTEM CONTROLLERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-25 | — | — | US | disclosed |
| US-4734416-A | ANTIHISTAMINES, CENTRAL NERVOUS SYSTEM CONTROLLING ACTION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-29 | — | — | US | disclosed |