Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825361 | 0.82 | ALDH1A1 (0.48) | ALDH1A1KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL10569125 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL10568270 | 0.80 | MEN1 (0.44) | ALDH1A1KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL10570922 | 0.77 | ALDH1A1 (0.44) | ALDH1A1KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL10573403 | 0.75 | MEN1 (0.48) | ALDH1A1MEN1KMT2APOLBMT-CO2 | |
| SCHEMBL10568837 | 0.75 | MEN1 (0.48) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL10569950 | 0.74 | ALDH1A1 (0.41) | ALDH1A1KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL16450894 | 0.73 | ALDH1A1 (0.38) | ALDH1A1KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL10567925 | 0.73 | MEN1 (0.36) | ALDH1A1KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL10570703 | 0.73 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2APOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4847285-A | 1-substituted phenyl-3-substituted methyl-pyrrolidine-2,5-diones and plant fungicide compositions containing same | THE DOW CHEMICAL COMPANY (US) | 1989-07-11 | — | — | US | disclosed |
| EP-0173284-A1 | Substituted 1-phenyl-3-methyl-pyrrolidindiones, their manufacture and use as fungicides | THE DOW CHEMICAL COMPANY (US) | 1986-03-05 | — | — | EP | disclosed |