Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.67 |
| ▸ | HPGD | P15428 | 5/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.55 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CLK2 | P49760 | 1/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | TOP2A | P11388 | 2/20 | 0.52 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636141 | 0.92 | KDM4E (0.69) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL312188 | 0.89 | ALDH1A1 (0.69) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL10573231 | 0.89 | KCNH2 (0.69) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL10570812 | 0.89 | KCNH2 (0.70) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL10575167 | 0.88 | KCNH2 (0.62) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL10571361 | 0.88 | KCNH2 (0.73) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL4368197 | 0.87 | KCNH2 (0.72) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL10573692 | 0.87 | KCNH2 (0.72) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9473967 | 0.87 | KDM4E (0.62) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL6370807 | 0.86 | KCNH2 (0.77) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4880806-A | BACTERICIDES | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1989-11-14 | — | — | US | disclosed |