Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10568367 | 0.86 | MEN1 (0.47) | MEN1OPRM1OPRD1KMT2AATM | |
| Dalbraminol SCHEMBL1255297 | 0.83 | MEN1 (0.51) | MEN1OPRM1OPRD1KMT2AATM | |
| SCHEMBL10671458 | 0.82 | CYP2D6 (0.43) | KMT2AADRB3ADRB2CYP1A2CYP2D6 | |
| SCHEMBL10839545 | 0.81 | MEN1 (0.49) | MEN1OPRM1OPRD1KMT2AATM | |
| SCHEMBL10838572 | 0.81 | MEN1 (0.55) | MEN1OPRM1OPRD1KMT2AATM | |
| SCHEMBL10839723 | 0.76 | MEN1 (0.58) | MEN1OPRM1OPRD1KMT2AATM | |
| SCHEMBL10669673 | 0.75 | HIF1A (0.38) | OPRM1TSHRLMNAADRB1ADRB2 | |
| SCHEMBL10670001 | 0.75 | HIF1A (0.47) | MEN1KMT2ATSHRLMNAADRB1 | |
| Hydrochloric Acid SCHEMBL7263799 | 0.75 | MEN1 (0.56) | MEN1OPRM1OPRD1KMT2AATM | |
| Hydrochloric Acid SCHEMBL11237704 | 0.75 | MEN1 (0.56) | MEN1OPRM1OPRD1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4880805-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-11-14 | — | — | US | claimed |
| US-4608383-A | Cardioactive pyrazole and imidazole aryloxypropanolamines | BOEHRINGER MANNHEIM GMBH (DE) | 1986-08-26 | — | — | US | claimed |
| US-4880805-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-11-14 | — | — | US | disclosed |
| US-4780474-A | DEFORMATION OF ERYTHROCYTES | BOEHRINGER MANNHEIM GMBH (DE) | 1988-10-25 | — | — | US | disclosed |
| EP-0172446-A2 | Utilisation of alkylenediamine derivatives for the treatment of irrigation troubles, and medicaments containing these compounds | Roche Diagnostics GmbH (DE) | 1986-02-26 | — | — | EP | disclosed |