Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 6/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10901101 | 1.00 | FAAH (0.44) | FAAHNAAAGAAMGAMSI | |
| SCHEMBL10900176 | 0.98 | GAA (0.44) | FAAHNAAAGAAMGAMSI | |
| SCHEMBL9808572 | 0.92 | MGAM (0.46) | FAAHNAAAGAAMGAMSI | |
| SCHEMBL27474440 | 0.89 | MGAM (0.52) | FAAHNAAAGAAMGAMSI | |
| SCHEMBL650012 | 0.89 | MGAM (0.52) | FAAHNAAAGAAMGAMSI | |
| SCHEMBL23041373 | 0.89 | MGAM (0.52) | FAAHNAAAGAAMGAMSI | |
| SCHEMBL27531643 | 0.89 | MGAM (0.52) | FAAHNAAAGAAMGAMSI | |
| SCHEMBL4595426 | 0.89 | MGAM (0.52) | FAAHNAAAGAAMGAMSI | |
| SCHEMBL6146968 | 0.89 | MGAM (0.52) | FAAHNAAAGAAMGAMSI | |
| SCHEMBL28173874 | 0.89 | MGAM (0.52) | FAAHNAAAGAAMGAMSI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4853393-A | HYPOTENSIVE AGENTS, ANTICOAGULANTS | CIBA-GEIGY CORPORATION (US) | 1989-08-01 | — | — | US | disclosed |
| EP-0194750-A1 | Dihydropyridine alkanol amines, process for their preparation and pharmaceutical compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-09-17 | — | — | EP | disclosed |
| US-4419518-A | VASODILATION, HYPOTENSIVE AGENTS | TOKYO TANABE CO. L.T.D. (JP) | 1983-12-06 | — | — | US | disclosed |