Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | HBB | P68871 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14344280 | 0.90 | KMT2A (0.54) | ATMKMT2APOLBMEN1CASP6 | |
| SCHEMBL14344274 | 0.87 | ATM (0.41) | ATMKMT2APOLBMEN1CASP6 | |
| SCHEMBL11687566 | 0.83 | ATM (0.38) | ATMKMT2APOLBMEN1CASP6 | |
| SCHEMBL11688940 | 0.81 | ATM (0.37) | ATMKMT2APOLBMEN1CASP6 | |
| SCHEMBL10572445 | 0.81 | KDM4E (0.42) | ATMKMT2APOLBMEN1CASP6 | |
| SCHEMBL29627789 | 0.81 | ATM (0.63) | ATMKMT2APOLBMEN1CASP6 | |
| SCHEMBL6919829 | 0.81 | ATM (0.63) | ATMKMT2APOLBMEN1CASP6 | |
| SCHEMBL11689845 | 0.79 | TSHR (0.40) | ATMKMT2APOLBMEN1CASP6 | |
| SCHEMBL11635781 | 0.79 | KDM4E (0.38) | ATMKMT2APOLBMEN1CASP6 | |
| Mequidox SCHEMBL193980 | 0.79 | KMT2A (0.39) | ATMKMT2APOLBMEN1CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111825612-B | Preparation method of 2, 3-quinoxaline dimethanol-1, 4-dioxide | 浦拉司科技（上海）有限责任公司 | 2021-11-30 | — | — | CN | claimed |
| CN-111825612-A | Preparation method of 2, 3-quinoxaline dimethanol-1, 4-dioxide | 浦拉司科技（上海）有限责任公司 | 2020-10-27 | — | — | CN | claimed |
| US-11439640-B2 | Pharmaceutical composition comprising substance inhibiting enzymatic activity of peroxiredoxin 2 as effective ingredient for treatment of colorectal cancer | EWHA University—Industry Collaboration Foundation (KR) | 2022-09-13 | — | — | US | disclosed |
| CN-111825612-B | Preparation method of 2, 3-quinoxaline dimethanol-1, 4-dioxide | 浦拉司科技（上海）有限责任公司 | 2021-11-30 | — | — | CN | disclosed |
| CN-111825612-B | Preparation method of 2, 3-quinoxaline dimethanol-1, 4-dioxide | 浦拉司科技（上海）有限责任公司 | 2021-11-30 | — | — | CN | disclosed |
| CN-111825612-A | Preparation method of 2, 3-quinoxaline dimethanol-1, 4-dioxide | 浦拉司科技（上海）有限责任公司 | 2020-10-27 | — | — | CN | disclosed |
| CN-111825612-A | Preparation method of 2, 3-quinoxaline dimethanol-1, 4-dioxide | 浦拉司科技（上海）有限责任公司 | 2020-10-27 | — | — | CN | disclosed |
| US-7312000-B2 | Electrolytic solution for secondary battery and secondary battery containing the same | NEC CORPORATION (JP) | 2007-12-25 | — | — | US | disclosed |
| US-4866175-A | REACTING BENZOFUROXAN WITH MALONIC ESTER, CYANO(ESTER OR AMIDE), KETO(ESTER OR AMIDE), DIKETONE, MALONONITRILE, OR NITRO COMPOUND | RESEARCH CORPORATION (US) | 1989-09-12 | — | — | US | disclosed |
| US-4343942-A | BACTERICIDES | RESEARCH CORPORATION (US) | 1982-08-10 | — | — | US | disclosed |
| US-4007184-A | BACTERICIDE, ANIMAL GROWTH REGULATOR | PFIZER INC. (US) | 1977-02-08 | — | — | US | disclosed |
| US-3931174-A | BACTERICIDE, GROWTH PROMOTERS | PFIZER INC. (US) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11439640-B2 | Pharmaceutical composition comprising substance inhibiting enzymatic activity of peroxiredoxin 2 as effective ingredient for treatment of colorectal cancer | TNKS, TNKS2, PRDX2 | ATM 1761/4885KMT2A 3795/4885POLB 889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.