SCHEMBL6919829

SCHEMBL6919829

[O-][n+]1c2ccccc2[n+]([O-])c2ccccc21

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.63
MEN1 O00255 3/20 0.59
KMT2A Q03164 3/20 0.59
POLB P06746 1/20 0.59
CASP6 P55212 1/20 0.59
CRHBP P24387 1/20 0.38
CRHR2 Q13324 1/20 0.38
KEAP1 Q14145 1/20 0.38
NFE2L2 Q16236 1/20 0.38
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
BCL2 P10415 1/20 0.36
KDM4E B2RXH2 4/20 0.35
ALDH1A1 P00352 1/20 0.35
HTT P42858 2/20 0.34
S1PR4 O95977 1/20 0.34
MAPT P10636 1/20 0.34
S1PR1 P21453 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
LMNA P02545 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29627789 1.00 ATM (0.63) ATMMEN1KMT2APOLBCASP6
SCHEMBL8904619 0.83 ATM (0.48) ATMMEN1KMT2APOLBCASP6
SCHEMBL8686338 0.81 MEN1 (0.56) ATMMEN1KMT2APOLBCASP6
SCHEMBL8785964 0.81 POLB (0.68) ATMMEN1KMT2APOLBCASP6
SCHEMBL8687527 0.81 MEN1 (0.56) ATMMEN1KMT2APOLBCASP6
Carbamic Acid SCHEMBL20269740 0.81 KMT2A (0.50) ATMMEN1KMT2APOLBCASP6
SCHEMBL14344280 0.79 KMT2A (0.54) ATMMEN1KMT2APOLBCASP6
SCHEMBL3084819 0.78 ATM (1.00) ATMMEN1KMT2APOLBCASP6
SCHEMBL8787510 0.77 MEN1 (0.57) ATMMEN1KMT2APOLBCASP6
SCHEMBL8785577 0.77 KMT2A (0.57) ATMMEN1KMT2APOLBCASP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998027969-A2 ANTIMICROBIAL PHENAZINE COMPOUNDS QUEEN'S UNIVERSITY AT KINGSTON (CA) 1998-07-02 WO claimed
US-5637591-A TREATMENT OF GINGIVITIS FUJI IMMUNOPHARMACEUTICALS CORP. (US) 1997-06-10 US claimed
JP-58116474-A None JP disclosed
JP-58083683-A None JP disclosed
JP-9100231-A None JP disclosed
US-20240145765-A1 ELECTRODE FOR NON-AQUEOUS ELECTROLYTE POWER STORAGE DEVICE, NON-AQUEOUS ELECTROLYTE POWER STORAGE DEVICE, AND METHOD FOR PRODUCING SAME ATTACCATO LIMITED LIABILITY COMPANY (JP) 2024-05-02 US disclosed
US-11958842-B2 Substituted phenazines and methods of treating cancer and bacterial diseases ADJUTEC PHARMA AS (NO) 2024-04-16 US disclosed
CN-114556616-A Electrode for nonaqueous electrolyte electricity storage device, and method for manufacturing same ATTACCATO合同会社 2022-05-27 CN disclosed
US-20210292313-A1 SUBSTITUTED PHENAZINES AND METHODS OF TREATING CANCER AND BACTERIAL DISEASES Rongved, Pål (NO) 2021-09-23 US disclosed
CN-113169293-A Electrode for nonaqueous electrolyte battery and nonaqueous electrolyte battery ATTACCATO合同会社 2021-07-23 CN disclosed
US-11046678-B2 Substituted phenazines and methods of treating cancer and bacterial diseases Rongved, Pål (NO) 2021-06-29 US disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed
US-4557934-A ALONG WITH A DIOL PYRROLIDONE OR AN AZACYCLOPENTAN-2-ONE THE PROCTER & GAMBLE COMPANY (US) 1985-12-10 US disclosed
US-4537776-A PERCUTANEOUS DELIVERY OF ANTIINFLAMMATORY AGENTS THE PROCTER & GAMBLE COMPANY (US) 1985-08-27 US disclosed
EP-0129285-A2 Penetrating topical pharmaceutical compositions containing N-(2-hydroxyethyl)pyrrolidone THE PROCTER & GAMBLE COMPANY (US) 1984-12-27 EP disclosed
EP-0129284-A2 Improved penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one THE PROCTER & GAMBLE COMPANY (US) 1984-12-27 EP disclosed
JP-S58116474-A PREPARATION OF PHENAZINE OXIDE TORAY IND INC 1983-07-11 JP disclosed
JP-S5883683-A PREPARATION OF PHENAZINE-5-OXIDE TORAY IND INC 1983-05-19 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11958842-B2 Substituted phenazines and methods of treating cancer and bacterial diseases TLR5, TOP2A, SCN5A ATM 1604/4885MEN1 212/4885KMT2A 953/4885
US-20210292313-A1 SUBSTITUTED PHENAZINES AND METHODS OF TREATING CANCER AND BACTERIAL DISEASES TLR5, TOP2A, SCN5A ATM 1604/4885MEN1 212/4885KMT2A 953/4885
US-11046678-B2 Substituted phenazines and methods of treating cancer and bacterial diseases NRAS, ABCB11, APC ATM 2198/4885MEN1 429/4885KMT2A 849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.