Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 3/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
| ▸ | GYPA | P02724 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21243724 | 0.88 | MEN1 (0.48) | MEN1KMT2AIDO1BCHEALDH1A1 | |
| SCHEMBL10573975 | 0.88 | MEN1 (0.48) | MEN1KMT2AIDO1BCHEALDH1A1 | |
| SCHEMBL10586008 | 0.83 | CYP3A4 (0.31) | IDO1 | |
| SCHEMBL26094036 | 0.82 | MEN1 (0.55) | MEN1KMT2AIDO1ALDH1A1CYP1A2 | |
| SCHEMBL6704224 | 0.80 | SLC6A2 (0.41) | PDE4DALDH1A1CYP2C19GYPA | |
| SCHEMBL6864596 | 0.80 | SLC6A2 (0.41) | PDE4DALDH1A1CYP2C19GYPA | |
| SCHEMBL7156144 | 0.80 | SLC6A2 (0.41) | PDE4DALDH1A1CYP2C19GYPA | |
| SCHEMBL6701050 | 0.80 | SLC6A2 (0.41) | PDE4DALDH1A1CYP2C19GYPA | |
| SCHEMBL7066247 | 0.78 | SLC6A2 (0.39) | MEN1KMT2APDE4DALDH1A1CYP2C19 | |
| SCHEMBL7037202 | 0.77 | GSTP1 (0.39) | MEN1KMT2AIDO1ALDH1A1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4861892-A | Method for synthesis of deoxymannojirimycin | G. D. SEARLE & CO. (US) | 1989-08-29 | — | — | US | disclosed |
| EP-0328508-A2 | Method for synthesis of deoxymannojirimycin | The NutraSweet Company (US) | 1989-08-16 | — | — | EP | disclosed |