Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.34 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.34 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.34 |
| ▸ | GJB2 | P29033 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6701050 | 0.90 | SLC6A2 (0.41) | SLC6A2TSHRCYP2C19PDE4DLGALS8 | |
| SCHEMBL6864596 | 0.90 | SLC6A2 (0.41) | SLC6A2TSHRCYP2C19PDE4DLGALS8 | |
| SCHEMBL7156144 | 0.90 | SLC6A2 (0.41) | SLC6A2TSHRCYP2C19PDE4DLGALS8 | |
| SCHEMBL6704224 | 0.90 | SLC6A2 (0.41) | SLC6A2TSHRCYP2C19PDE4DLGALS8 | |
| SCHEMBL7154227 | 0.81 | SLC6A2 (0.44) | SLC6A2TSHRCYP2C19PDE4DLGALS8 | |
| SCHEMBL7642620 | 0.81 | SLC6A2 (0.44) | SLC6A2TSHRCYP2C19PDE4DLGALS8 | |
| SCHEMBL7066725 | 0.79 | SLC6A2 (0.37) | SLC6A2TSHRCYP2C19PDE4DLGALS8 | |
| SCHEMBL7064868 | 0.78 | LGALS8 (0.42) | TSHRLGALS8ALDH1A1 | |
| SCHEMBL10575985 | 0.78 | MEN1 (0.39) | CYP2C19PDE4DALDH1A1MEN1KMT2A | |
| SCHEMBL21243724 | 0.78 | MEN1 (0.48) | ALDH1A1MEN1KMT2APTPN1CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030236229-A1 | Novel 3,5,and/or 6 substituted analogues of swainsonine processes for their preparation and their use as therapeutic agents | GLYCODESIGN INC. (CA) | 2003-12-25 | — | — | US | disclosed |
| US-20020099065-A1 | Novel 3, 5, and/or 6 substituted analogues of swainsonine, processes for their preparation and their use as therapeutic agents | GLYCODESIGN INC. (CA) | 2002-07-25 | — | — | US | disclosed |
| US-6048870-A | MANNOSIDASE INHIBITOR; IMMUNOSTIMULANT | GLYCODESIGN (CA) | 2000-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236229-A1 | Novel 3,5,and/or 6 substituted analogues of swainsonine processes for their preparation and their use as therapeutic agents | WDR77, WDR3, WDR5 | SLC6A2 1586/4885TSHR 4771/4885CYP2C19 4312/4885 |
| US-20020099065-A1 | Novel 3, 5, and/or 6 substituted analogues of swainsonine, processes for their preparation and their use as therapeutic agents | WDR5, WDR3, WDR77 | SLC6A2 563/4885TSHR 4315/4885CYP2C19 3626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.