SCHEMBL10577620

SCHEMBL10577620

N[C@@]1(C(=O)O)C[C@H]1C1CC1

nearest known ligand 0.62

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GRM1 Q13255 4/20 0.62
GRM2 Q14416 9/20 0.53
GRM4 Q14833 7/20 0.53
GRM6 O15303 7/20 0.53
GRM5 P41594 5/20 0.53
GRM3 Q14832 4/20 0.53
SLC6A4 P31645 1/20 0.41
GRM8 O00222 4/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25660648 1.00 GRM1 (0.62) GRM1GRM2GRM4GRM6GRM5
SCHEMBL670022 1.00 GRM1 (0.62) GRM1GRM2GRM4GRM6GRM5
SCHEMBL5522614 0.81 GRM1 (0.42) GRM1GRM2GRM4GRM6GRM5
SCHEMBL25910070 0.81 GRM1 (0.42) GRM1GRM2GRM4GRM6GRM5
SCHEMBL13319986 0.77 GRM1 (1.00) GRM1GRM2GRM4GRM6GRM5
SCHEMBL6738759 0.77 GRM1 (1.00) GRM1GRM2GRM4GRM6GRM5
SCHEMBL669419 0.74 GRM2 (0.47) GRM1GRM2GRM4GRM6GRM5
SCHEMBL3375726 0.74 GRM1 (0.38) GRM1GRM2GRM4GRM6GRM5
SCHEMBL32674074 0.74 GRM1 (0.38) GRM1GRM2GRM4GRM6GRM5
SCHEMBL10093291 0.70 GRM1 (0.35) GRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4851035-A Composition for inhibition of ethylene production in plants THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY, STANFORD UNIVERSITY (US) 1989-07-25 US claimed