Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 4/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 6/20 | 0.35 |
| ▸ | GRM5 | P41594 | 5/20 | 0.35 |
| ▸ | GRM6 | O15303 | 2/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.35 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.35 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.33 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5522614 | 1.00 | GRM1 (0.42) | GRM1GRM2GRM5GRM6GRM4 | |
| SCHEMBL25660648 | 0.81 | GRM1 (0.62) | GRM1GRM2GRM5GRM6GRM4 | |
| SCHEMBL670022 | 0.81 | GRM1 (0.62) | GRM1GRM2GRM5GRM6GRM4 | |
| SCHEMBL10577620 | 0.81 | GRM1 (0.62) | GRM1GRM2GRM5GRM6GRM4 | |
| SCHEMBL24376200 | 0.80 | GRM1 (0.36) | GRM1GRM2GRM5GRM6GRM4 | |
| SCHEMBL32674074 | 0.74 | GRM1 (0.38) | GRM1GRM2GRM5GRM6GRM4 | |
| SCHEMBL3375726 | 0.74 | GRM1 (0.38) | GRM1GRM2GRM5GRM6GRM4 | |
| SCHEMBL28515430 | 0.73 | GRM1 (0.35) | GRM1SLC6A12SLC6A11 | |
| SCHEMBL15654044 | 0.73 | KDM4E (0.31) | — | |
| SCHEMBL10093291 | 0.70 | GRM1 (0.35) | GRM1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141300-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2023-07-27 | — | — | WO | disclosed |