Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | F9 | P00740 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10574974 | 0.91 | MAPT (0.44) | KDM4EPDE10AKMT2AMAPTPKM | |
| SCHEMBL10572400 | 0.91 | KMT2A (0.40) | KDM4EPDE10AKMT2APOLBMAPT | |
| SCHEMBL10576991 | 0.87 | KMT2A (0.43) | KDM4EPDE10AKMT2APOLBMAPT | |
| SCHEMBL10574811 | 0.86 | APEX1 (0.54) | KDM4EPDE10APOLBMAPTPKM | |
| SCHEMBL10579145 | 0.85 | CACNA1H (0.39) | PDE10AKMT2APOLBSCN10AMAPT | |
| SCHEMBL10574200 | 0.84 | MAPT (0.55) | KDM4EPDE10AKMT2APOLBMAPT | |
| SCHEMBL10573979 | 0.83 | GAA (0.51) | KDM4EMAPTPKMTDP1 | |
| SCHEMBL10578941 | 0.83 | MAPT (0.51) | KDM4EKMT2APOLBSCN10AMAPT | |
| SCHEMBL10576299 | 0.82 | HDAC1 (0.53) | PDE10AKMT2APOLBMAPTMEN1 | |
| SCHEMBL10574963 | 0.82 | GHSR (0.38) | KDM4EKMT2APOLBMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882342-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-11-21 | — | — | US | disclosed |
| EP-0266558-A2 | 5-Alkylbenzimidazoles, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1988-05-11 | — | — | EP | disclosed |