Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | PNP | P00491 | 1/20 | 0.46 |
| ▸ | PI4KA | P42356 | 2/20 | 0.43 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.43 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24725165 | 0.75 | APP (0.50) | APPPNPPI4KAPI4K2BPI4K2A | |
| SCHEMBL10579911 | 0.73 | AURKA (0.33) | — | |
| SCHEMBL28526402 | 0.73 | APP (0.55) | HSD17B10APPKDM4EMEN1KMT2A | |
| SCHEMBL1518098 | 0.72 | PDE10A (0.33) | — | |
| SCHEMBL248683 | 0.71 | ELANE (0.50) | HSD17B10APPKDM4EMEN1KMT2A | |
| SCHEMBL8089268 | 0.71 | HSD17B10 (0.50) | BACE1HSD17B10PNPMAPTKDM4E | |
| SCHEMBL2463445 | 0.71 | APP (0.56) | APPMAPTKDM4EKMT2AELANE | |
| SCHEMBL17807836 | 0.70 | BACE1 (0.58) | BACE1HSD17B10APPPI4KAPI4K2B | |
| SCHEMBL16818759 | 0.70 | BACE1 (0.58) | BACE1HSD17B10APPMAPTKDM4E | |
| SCHEMBL24433885 | 0.70 | HDAC8 (0.49) | HSD17B10MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4879377-A | Nucleoside process | BRISTOL-MYERS COMPANY (US) | 1989-11-07 | — | — | US | disclosed |
| EP-0145978-B1 | NUCLEOSIDE PROCESS | Bristol-Myers Company (US) | 1989-04-19 | — | — | EP | disclosed |
| US-4625020-A | Nucleoside process | BRISTOL-MYERS COMPANY (US) | 1986-11-25 | — | — | US | disclosed |
| EP-0145978-A2 | Nucleoside process | Bristol-Myers Company (US) | 1985-06-26 | — | — | EP | disclosed |