Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.50 |
| ▸ | PNP | P00491 | 1/20 | 0.47 |
| ▸ | PI4KA | P42356 | 2/20 | 0.45 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.45 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.45 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11760490 | 0.76 | PNP (0.60) | PNPPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL10580470 | 0.75 | BACE1 (0.51) | APPPNPPI4KAPI4K2BPI4K2A | |
| Hydrochloric Acid SCHEMBL5478228 | 0.72 | APP (0.67) | APP | |
| SCHEMBL2271787 | 0.71 | L3MBTL1 (0.47) | — | |
| SCHEMBL11678932 | 0.70 | PNP (0.60) | APPPNP | |
| Sulfuric Acid SCHEMBL5467550 | 0.69 | APP (0.58) | APP | |
| SCHEMBL10485673 | 0.68 | APP (0.64) | APP | |
| SCHEMBL6024935 | 0.67 | APP (0.59) | APP | |
| SCHEMBL12322087 | 0.67 | APP (1.00) | APP | |
| SCHEMBL248683 | 0.66 | ELANE (0.50) | APPRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023028338-A2 | MANNOSE 6-PHOSPHATE OR ASGPR RECEPTOR BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2023-03-02 | — | — | WO | disclosed |
| WO-2022235699-A2 | POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |