Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10582404 | 0.92 | SMN1; SMN2 (0.44) | SMN1; SMN2CYP2C9CYP2C19HPGDNPC1 | |
| SCHEMBL10583968 | 0.91 | SMN1; SMN2 (0.39) | SMN1; SMN2CYP2C9CYP2C19HPGDNPC1 | |
| SCHEMBL10579484 | 0.91 | CTDSP1 (0.46) | SMN1; SMN2CYP2C9CYP2C19HPGDNPC1 | |
| SCHEMBL10582790 | 0.87 | CTDSP1 (0.40) | SMN1; SMN2NPC1RAB9ACTDSP1ALDH1A1 | |
| SCHEMBL10581310 | 0.85 | NAMPT (0.45) | SMN1; SMN2CYP2C9CYP2C19NPC1RAB9A | |
| SCHEMBL10579292 | 0.83 | KDM4E (0.48) | SMN1; SMN2CYP2C9CYP2C19HPGDNPC1 | |
| SCHEMBL10582238 | 0.82 | ENPP2 (0.50) | CYP2C19NPC1ALDH1A1KMT2AMAPT | |
| SCHEMBL10579830 | 0.82 | ATM (0.49) | SMN1; SMN2CYP2C9CYP2C19NPC1CYP1A2 | |
| SCHEMBL10581128 | 0.82 | RAD51 (0.48) | CYP1A2CTDSP1ALDH1A1KMT2ALMNA | |
| SCHEMBL10580263 | 0.81 | MAPT (0.50) | SMN1; SMN2CTDSP1ALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4843151-A | RED/YELLOW DYES FOR NATURAL AND SYNTHETIC POLYAMIDES USING AN AQUEOUS BATH; COLORFASTNESS | CIBA-GEIGY CORPORATION (US) | 1989-06-27 | — | — | US | disclosed |