⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31604523 | 0.73 | — | — | |
| SCHEMBL3191459 | 0.71 | — | — | |
| SCHEMBL15459135 | 0.71 | — | — | |
| SCHEMBL9763813 | 0.69 | ALDH1A1 (0.43) | — | |
| SCHEMBL17361362 | 0.69 | ALDH1A1 (0.43) | — | |
| SCHEMBL26477012 | 0.69 | ALDH1A1 (0.30) | — | |
| SCHEMBL8410037 | 0.67 | TSHR (0.33) | — | |
| SCHEMBL4197507 | 0.67 | — | — | |
| SCHEMBL701581 | 0.67 | — | — | |
| SCHEMBL400148 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 456 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260098048-A1 | IMPROVED PROCESS FOR THE PREPARATION OF RISDIPLAM AND ITS INTERMEDIATES | NATCO PHARMA LTD (IN) | 2026-04-09 | — | — | US | claimed |
| US-20240182493-A1 | PROCESS | HOFFMANN-LA ROCHE INC. (US) | 2024-06-06 | — | — | US | claimed |
| WO-2024069646-A1 | IMPROVED PROCESS FOR THE PREPARATION OF RISDIPLAM AND ITS INTERMEDIATES | NATCO PHARMA LIMITED (IN) | 2024-04-04 | — | — | WO | claimed |
| EP-4308578-A2 | PROCESS FOR PREPARING RISDIPLAM | F. Hoffmann-La Roche AG (CH) | 2024-01-24 | — | — | EP | claimed |
| CN-117015546-A | Process for preparing Li Sipu blue | 豪夫迈·罗氏有限公司 | 2023-11-07 | — | — | CN | claimed |
| CN-111348992-A | Novel method for synthesizing 1-bromo-2, 2-dimethoxypropane | 北京富百科生物技术有限公司 | 2020-06-30 | — | — | CN | claimed |
| CN-107739328-A | For synthesizing preparation methods of the Ba Rui for the key intermediate 1 of Buddhist nun | 厦门海乐景生化有限公司 | 2018-02-27 | — | — | CN | claimed |
| CN-104262121-A | Method for synthesizing 1,3-dibromo-2,2-dimethoxy propane | SUZHOU VIVOTIDE BIOTECHNOLOGIES CO LTD | 2015-01-07 | — | — | CN | claimed |
| CN-122055363-A | Compounds and methods for modulating splicing | 雷密克斯医疗公司 | 2026-05-15 | — | — | CN | disclosed |
| EP-4724438-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | Remix Therapeutics Inc. (US) | 2026-04-15 | — | — | EP | disclosed |
| US-20260098048-A1 | IMPROVED PROCESS FOR THE PREPARATION OF RISDIPLAM AND ITS INTERMEDIATES | NATCO PHARMA LTD (IN) | 2026-04-09 | — | — | US | disclosed |
| EP-4698541-A1 | THIENO[3,2-B]PYRIDINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2026-02-25 | — | — | EP | disclosed |
| EP-4288426-B1 | QUINOXALINE DERIVATIVES AND USES THEREOF | BLACK DIAMOND THERAPEUTICS INC (US) | 2026-02-04 | — | — | EP | disclosed |
| US-20260008790-A1 | COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY | HOFFMANN-LA ROCHE INC. (US) | 2026-01-08 | — | — | US | disclosed |
| EP-0329711-A1 | 2,4,4-TRI- AND 2,2,4,4-TETRA SUBSTITUTED-1,3-DIOXOLANE COMPOUNDS | SCHERING CORPORATION (US) | 1989-08-30 | — | — | EP | disclosed |
| US-4788190-A | 2,4,4-tri- and 2,2,4,4-tetra substituted-1,3-dioxolane antifungal, antiallergy compounds | SCHERING CORPORATION (US) | 1988-11-29 | — | — | US | disclosed |
| EP-0278105-A1 | 2,4,4-Tri- and 2,2,4,4-tetra-substituted-1,3-dioxolane | SCHERING CORPORATION (US) | 1988-08-17 | — | — | EP | disclosed |
| WO-1988005048-A1 | 2,4,4-TRI- AND 2,2,4,4-TETRA SUBSTITUTED-1,3-DIOXOLANE COMPOUNDS | SCHERING CORPORATION (US) | 1988-07-14 | — | — | WO | disclosed |
| US-4411899-A | Substituted derivatives of amino alkane diols as gastric secretion inhibitors | MERCK & CO., INC. (US) | 1983-10-25 | — | — | US | disclosed |
| EP-0082376-A2 | Substituted derivatives of amino alkane diols as gastric secretion inhibitors | MERCK & CO. INC. (US) | 1983-06-29 | — | — | EP | disclosed |