Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.49 |
| ▸ | CTSC | P53634 | 1/20 | 0.43 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.40 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9358482 | 0.83 | TEAD1 (0.55) | PTGS1POLBTRPV1TEAD1MAPT | |
| SCHEMBL9362813 | 0.81 | MAPT (0.50) | POLBSMN1; SMN2KDM4EALDH1A1TP53 | |
| SCHEMBL10585355 | 0.78 | MEN1 (0.47) | SMN1; SMN2TRPV1MAPT | |
| SCHEMBL30114377 | 0.76 | PTGS1 (0.60) | PTGS1 | |
| SCHEMBL10585521 | 0.74 | KDM4E (0.55) | PTGS1CTSCPOLBKDM4EALDH1A1 | |
| SCHEMBL30503074 | 0.74 | NPC1 (0.45) | PTGS1TRPV1MAPT | |
| SCHEMBL25876884 | 0.74 | NPC1 (0.45) | PTGS1TRPV1MAPT | |
| SCHEMBL23337972 | 0.73 | TRPV1 (0.42) | RPS6KA3POLBSMN1; SMN2ALDH1A1TRPV1 | |
| SCHEMBL5929115 | 0.72 | TRPV1 (0.58) | TRPV1 | |
| SCHEMBL24497427 | 0.72 | TEAD1 (0.50) | PTGS1TRPV1TEAD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320448-A2 | 3-Aminobenzoyl phenyl urea | CIBA-GEIGY AG (CH) | 1989-06-14 | — | — | EP | claimed |