Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | XPO1 | O14980 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.40 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | BCR | P11274 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22719743 | 0.83 | TEAD1 (0.60) | TEAD1POLBGAAXPO1TRPV1 | |
| SCHEMBL10584876 | 0.83 | PTGS1 (0.49) | TEAD1PTGS1POLBTRPV1MAPT | |
| SCHEMBL29505063 | 0.80 | TEAD1 (0.52) | TEAD1POLBGAAXPO1TRPV1 | |
| SCHEMBL22719666 | 0.80 | TEAD1 (0.52) | TEAD1POLBGAAXPO1TRPV1 | |
| SCHEMBL9358514 | 0.78 | ALDH1A1 (0.50) | TEAD1GAAKDRMAPTABL1 | |
| SCHEMBL10581849 | 0.77 | ALDH1A1 (0.50) | POLBGAAMAPT | |
| SCHEMBL30114377 | 0.76 | PTGS1 (0.60) | PTGS1SCN9A | |
| SCHEMBL24497427 | 0.74 | TEAD1 (0.50) | TEAD1PTGS1TRPV1MAPK10 | |
| SCHEMBL29648357 | 0.74 | TEAD1 (0.50) | TEAD1PTGS1TRPV1MAPK10 | |
| SCHEMBL10585521 | 0.74 | KDM4E (0.55) | PTGS1POLBGAAMAPTTNNI3K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320448-A2 | 3-Aminobenzoyl phenyl urea | CIBA-GEIGY AG (CH) | 1989-06-14 | — | — | EP | claimed |
| EP-0320448-B1 | 3-Aminobenzoyl phenyl urea | CIBA GEIGY AG (CH) | 1994-12-28 | — | — | EP | disclosed |
| US-4946854-A | PESTICIDES | CIBA-GEIGY CORPORATION (US) | 1990-08-07 | — | — | US | disclosed |
| EP-0320448-A2 | 3-Aminobenzoyl phenyl urea | CIBA-GEIGY AG (CH) | 1989-06-14 | — | — | EP | disclosed |