Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 14/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808728 | 0.73 | CYP19A1 (0.39) | CYP19A1 | |
| SCHEMBL10761825 | 0.73 | CYP19A1 (0.42) | CYP19A1CYP3A4CYP3A5LMNAMEN1 | |
| SCHEMBL9488032 | 0.69 | CYP19A1 (0.47) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL125811 | 0.66 | CYP19A1 (0.61) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL10731498 | 0.66 | CYP19A1 (0.51) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL11095244 | 0.65 | CYP19A1 (0.50) | CYP19A1CYP3A4CYP3A5MEN1KMT2A | |
| SCHEMBL11910304 | 0.64 | SLC6A2 (0.57) | CYP3A4ALDH1A1LMNAMAPTSLC6A4 | |
| SCHEMBL3374829 | 0.63 | SLC6A2 (0.51) | CYP19A1CYP3A4SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL22125029 | 0.63 | SLC6A2 (0.55) | CYP3A4ALDH1A1LMNAMAPTSLC6A4 | |
| SCHEMBL9651054 | 0.63 | CYP19A1 (1.00) | CYP19A1CYP3A4CYP3A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304171-A1 | Pyrimidine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-02-22 | — | — | EP | disclosed |