Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 16/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11093646 | 0.84 | CYP19A1 (0.50) | CYP19A1CYP3A4CYP3A5KMT2A | |
| SCHEMBL17172185 | 0.80 | CYP3A4 (0.39) | CYP19A1CYP3A4CYP3A5CYP17A1 | |
| SCHEMBL11092452 | 0.79 | ABL1 (0.38) | — | |
| SCHEMBL11094188 | 0.77 | CYP19A1 (0.50) | CYP19A1CYP3A4CYP3A5CYP17A1MEN1 | |
| SCHEMBL125811 | 0.74 | CYP19A1 (0.61) | CYP19A1CYP3A4CYP3A5CYP17A1 | |
| SCHEMBL10586952 | 0.72 | CYP19A1 (0.46) | CYP19A1CYP3A4CYP3A5CYP17A1 | |
| SCHEMBL21216519 | 0.69 | MEN1 (0.48) | CYP3A4CYP17A1MEN1KMT2A | |
| SCHEMBL22623915 | 0.69 | KMT2A (0.48) | CYP3A4CYP17A1MEN1KMT2A | |
| SCHEMBL10834654 | 0.68 | CYP19A1 (0.42) | CYP19A1CYP3A4 | |
| SCHEMBL9651054 | 0.68 | CYP19A1 (1.00) | CYP19A1CYP3A4CYP3A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0109299-A2 | 1,1-Disubstituted-2-heterocyclic ethanol derivatives | ELI LILLY AND COMPANY (US) | 1984-05-23 | — | — | EP | claimed |
| EP-0109299-A2 | 1,1-Disubstituted-2-heterocyclic ethanol derivatives | ELI LILLY AND COMPANY (US) | 1984-05-23 | — | — | EP | disclosed |