Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 9/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 9/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 9/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 9/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16409353 | 0.75 | CHRM2 (0.57) | GRIN1GRIN2ACHRM2CHRM4CHRM5 | |
| SCHEMBL1690206 | 0.73 | CHRM2 (0.55) | GRIN1GRIN2ACHRM2CHRM4CHRM5 | |
| SCHEMBL19308438 | 0.73 | CHRM2 (0.55) | GRIN1GRIN2ACHRM2CHRM4CHRM5 | |
| SCHEMBL16409291 | 0.70 | CHRM2 (0.51) | GRIN1GRIN2ACHRM2CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL10391535 | 0.69 | GRIN1 (0.43) | GRIN1GRIN2ACHRM2CHRM4CHRM5 | |
| SCHEMBL8040886 | 0.68 | GRIN1 (0.55) | GRIN1GRIN2ACHRM2CHRM4CHRM5 | |
| SCHEMBL7108497 | 0.67 | GRIN1 (0.43) | GRIN1GRIN2ACHRM2CHRM4CHRM5 | |
| SCHEMBL2220242 | 0.67 | GRIN1 (0.43) | GRIN1GRIN2ACHRM2CHRM4CHRM5 | |
| SCHEMBL15571397 | 0.67 | GRIN1 (0.40) | GRIN1GRIN2ACHRM2CHRM4CHRM5 | |
| SCHEMBL58980 | 0.66 | SLC6A2 (0.62) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309425-A2 | New heterocyclic derivatives | ISTITUTO DE ANGELI S.p.A. (IT) | 1989-03-29 | — | — | EP | disclosed |