SCHEMBL2220242

SCHEMBL2220242

c1ccc(C23CCCCC2O3)cc1

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GRIN1 Q05586 2/20 0.43
GRIN2A Q12879 2/20 0.43
CHRM2 P08172 7/20 0.40
CHRM4 P08173 7/20 0.40
CHRM5 P08912 7/20 0.40
CHRM1 P11229 7/20 0.40
CHRM3 P20309 7/20 0.40
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7108497 1.00 GRIN1 (0.43) GRIN1GRIN2ACHRM2CHRM4CHRM5
SCHEMBL11369540 0.94 MAPK1 (0.39) GRIN1GRIN2A
SCHEMBL6347170 0.90 SLC6A2 (0.42) GRIN1GRIN2ACHRM2CHRM4CHRM5
SCHEMBL6351533 0.84 SLC6A2 (0.40) SLC6A2SLC6A4SLC6A3
SCHEMBL13221438 0.81 SLC6A3 (0.40) SLC6A2SLC6A4SLC6A3
SCHEMBL38663972 0.80 SLC6A3 (0.47) SLC6A2SLC6A4SLC6A3
SCHEMBL22261434 0.79 NPC1 (0.34) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL15823722 0.79 CHRNA1 (0.35) GRIN1GRIN2ASLC6A2SLC6A4SLC6A3
SCHEMBL27479696 0.78 GRIN1 (0.33) GRIN1GRIN2ACHRM2CHRM4CHRM5
SCHEMBL6848854 0.76 SLC6A4 (0.52) CHRM2CHRM1SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111217769-B Method for synthesizing epoxy compound by catalyzing olefin epoxy by using nano alumina 华南理工大学 2023-04-21 CN claimed
EP-1276733-A1 METHOD FOR EPOXIDIZING OLEFINS MERCK PATENT GmbH (DE) 2003-01-22 EP claimed
WO-2001083466-A1 METHOD FOR EPOXIDIZING OLEFINS MERCK PATENT GMBH (DE) 2001-11-08 WO claimed
CN-118459511-A Metallocene complex and application thereof, preparation method of olefin polymer and ethylene/alpha-olefin copolymer 贝欧亿(山东)新材料有限公司 2024-08-09 CN disclosed
CN-111217769-B Method for synthesizing epoxy compound by catalyzing olefin epoxy by using nano alumina 华南理工大学 2023-04-21 CN disclosed
EP-2216312-B1 PROCESS FOR PRODUCING ORGANIC COMPOUND M TECHNIQUE CO LTD (JP) 2019-05-01 EP disclosed
US-8877930-B2 Continuous flow synthesis of amino alcohols using microreactors MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2014-11-04 US disclosed
US-8877930-B2 Continuous flow synthesis of amino alcohols using microreactors MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2014-11-04 US disclosed
US-8592498-B2 Method for producing organic compound and organic compound obtained by the method M. TECHNIQUE CO., LTD. (JP) 2013-11-26 US disclosed
US-8227640-B2 Palladium catalysts INSTITUTE OF BIOENGINEERING AND NANOTECHNOLOGY (SG) 2012-07-24 US disclosed
US-20110178199-A1 METHOD FOR PRODUCING ORGANIC COMPOUND AND ORGANIC COMPOUND OBTAINED BY THE METHOD M. TECHNIQUE CO., LTD. (JP) 2011-07-21 US disclosed
CN-1198157-A Dinaphtazepinium salts useful as enantioselective epoxidation catalysts UNIV SHEFFIELD (GB) 1998-11-04 CN disclosed
WO-1998033786-A1 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1998-08-06 WO disclosed
EP-0843664-A1 DINAPHTAZEPINIUM SALTS USEFUL AS ENANTIOSELECTIVE EPOXIDATION CATALYSTS The University of Sheffield (GB) 1998-05-27 EP disclosed
WO-1998015544-A1 CATALYTIC ASYMMETRIC EPOXIDATION COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1998-04-16 WO disclosed
WO-1997006147-A1 DINAPHTAZEPINIUM SALTS USEFUL AS ENANTIOSELECTIVE EPOXIDATION CATALYSTS THE UNIVERSITY OF SHEFFIELD (GB) 1997-02-20 WO disclosed
EP-0272421-B1 COLOR STABILIZED IRRADIATED POLYCARBONATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 1993-03-03 EP disclosed
US-4894401-A DISCOLORATION INHIBITION GENERAL ELECTRIC COMPANY (US) 1990-01-16 US disclosed
US-4873278-A Inhibition of irradiation yellowing in polysulfone compositions GENERAL ELECTRIC COMPANY (US) 1989-10-10 US disclosed
EP-0272421-A2 Color stabilized irradiated polycarbonate compositions GENERAL ELECTRIC COMPANY (US) 1988-06-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110178199-A1 METHOD FOR PRODUCING ORGANIC COMPOUND AND ORGANIC COMPOUND OBTAINED BY THE METHOD OR10J3, PORCN, ABCG2 GRIN1 3663/4885GRIN2A 3942/4885CHRM2 2707/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.