Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIMP3 | P35625 | 2/20 | 0.44 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.37 |
| ▸ | CHAT | P28329 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10585378 | 0.88 | TIMP3 (0.35) | TIMP3RAPGEF4CASP6ALDH1A1KDM4E | |
| SCHEMBL9422589 | 0.84 | LRRK2 (0.45) | CASP6ALDH1A1MAPTKMT2ASNCA | |
| SCHEMBL7899594 | 0.80 | CDK2 (0.42) | RAPGEF4CASP6ALDH1A1KDM4EPOLB | |
| SCHEMBL114494 | 0.78 | CHAT (0.52) | TIMP3RAPGEF4CASP6ALDH1A1KDM4E | |
| SCHEMBL9484849 | 0.78 | CA12 (0.47) | TIMP3RAPGEF4CASP6ALDH1A1KDM4E | |
| SCHEMBL30268659 | 0.78 | CHAT (0.52) | TIMP3RAPGEF4CASP6ALDH1A1KDM4E | |
| SCHEMBL10777078 | 0.76 | TIMP3 (0.40) | TIMP3RAPGEF4CASP6ALDH1A1KDM4E | |
| SCHEMBL7684666 | 0.76 | SNCA (0.42) | TIMP3ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL9462489 | 0.75 | CHAT (0.44) | TIMP3RAPGEF4CASP6ALDH1A1KDM4E | |
| SCHEMBL7717587 | 0.75 | TIMP3 (0.39) | TIMP3RAPGEF4CASP6ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321784-A2 | Formazane dyes containing heavy metals, process for their preparation and their use in dyeing and printing fibrous materials | BAYER AG (DE) | 1989-06-28 | — | — | EP | disclosed |