TIMP3 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL1902159	1.00	6/20
SCHEMBL3359656	1.00	6/20
SCHEMBL11341928	0.63	6/20
SCHEMBL7223972	0.62	6/20
SCHEMBL11342408	0.62	6/20
SCHEMBL11344916	0.62	6/20
SCHEMBL11335401	0.61	6/20
SCHEMBL11347634	0.61	6/20
SCHEMBL4027006	0.60	6/20
SCHEMBL11339227	0.59	6/20
SCHEMBL11339145	0.58	6/20
SCHEMBL11351829	0.58	6/20
SCHEMBL11343060	0.56	6/20
SCHEMBL11351805	0.56	6/20
SCHEMBL11205429	0.56	6/20
SCHEMBL11350583	0.55	6/20
SCHEMBL11351833	0.55	6/20
SCHEMBL11352224	0.55	6/20
SCHEMBL11337777	0.54	6/20
SCHEMBL11347076	0.54	6/20

Clinical trials — most relevant to TIMP3 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Estimation of MMP-8 Levels in GCF and Serum and Its Correlation With Wound Healing and Clinical Outcomes After Coronally Advanced Flap and Subepithelial Connective Tissue Graft for Root Coverage in Recession Defects: A CLINICO-BIOCHEMICAL STUDY	PHASE4	SUSPENDED
Effect of Pioglitazone on TIMP-3 and TACE in Type 2 Diabetes	PHASE4	COMPLETED
Hyaluronic Acid vs Mitomycin-C in External Dacryocystorhinostomy	PHASE4	NOT_YET_RECRUITING
Biomarkers and Antithrombotic Treatment in Cervical Artery Dissection - TREAT-CAD	PHASE3	COMPLETED
Sputum Matrix Metalloproteinases (MMP) mRNA and Montelukast	PHASE2	COMPLETED
Allogeneic Adipose Tissue-derived Mesenchymal Stem Cells in Ischemic Stroke	PHASE2	UNKNOWN
Synvisc to Treat Osteoarthritis of the Temporomandibular Joint	PHASE2	COMPLETED
A Study of Sorafenib in Patients With Chemonaive Metastatic Uveal Melanoma	PHASE2	UNKNOWN
A Phase I Study of Oral COL-3 (NSC-683551), a Matrix Metalloproteinase Inhibitor, in Patients With Refractory Metastatic Cancer	PHASE1	COMPLETED
Apoptotic Changes in Gingiva Caused by Smoking	nan	COMPLETED
Abnormal 3-D MRI Flow Patterns in Adolescents Patients With Bicuspid Aortic Valve	nan	COMPLETED
Investigation of Substrates Associated With the Recurrence of Atrial Fibrillation After PV Cryoablation	nan	COMPLETED
Matrix Metalloproteinases After Surgery and/or Radiofrequency Ablation in Patients With Liver Metastases From Colorectal Cancer	nan	COMPLETED
Re-evaluation of Some Old Rheumatoid Arthritis Therapy: A Randomized Controlled Trial	nan	COMPLETED
Influence of Statins in Artery Aneurysms	nan	UNKNOWN
Multicentre Trial Of Serum Levels Of MMP-9 As A Biomarker Of Endoleak	nan	COMPLETED
Plasma Levels of Matrix Metalloproteinases (MMPs) and Degree of DNA Fragmentation in Pseudoexfoliation (PEX) Glaucoma	nan	COMPLETED
Evaluation of Different Serum Cartilage Biomarkers in the Acute Response to Walking and Cycling in Healthy Male Subjects	nan	AVAILABLE
Plasma and Scarring of Diabetic Ulcers	nan	COMPLETED
Biomarkers in Post Thrombotic Syndrome	nan	COMPLETED
Platelet Rich Plasma for Treatment of Facial Photoaging: A Double-blind, Randomized, Split-face Study	nan	UNKNOWN
The Effect of Eplerenone and Atorvastatin on Markers of Collagen Turnover in Diastolic Heart Failure	nan	COMPLETED
Role of Extracellular Matrix in the Development of Airway Remodeling in Asthma	nan	UNKNOWN
Role and Expression of MXRA5 in Placental Connective Tissue Remodelling in Preeclampsia	nan	UNKNOWN
Serum COMP and MMP-3 in Knee Osteoarthritis	nan	NOT_YET_RECRUITING
Role of A Disintegrin and Metalloproteinase (ADAM) in Epithelial Dysfunction	nan	COMPLETED
Mechanisms Underlying SGLT2i Kidney Effect in DKD Progression	nan	NOT_YET_RECRUITING
Pathology, Venous Disease, and Clinical Correlations	nan	UNKNOWN
Elevated Plasma Levels of TIMP-1 in Patients With Rotator Cuff Tear	nan	COMPLETED
Influence of Short AV Delay Permanent Pacing on Matrix Metalloproteinase Levels	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a TIMP3 binder may also engage these)

Protein	Name	Similarity
Q5PXZ9	—	1.000	Q5PXZ9 →
P61269	—	1.000	P61269 →
P39876	—	1.000	P39876 →
P79121	—	1.000	P79121 →
Q9W6B4	—	1.000	Q9W6B4 →
Q9TUL9	—	1.000	Q9TUL9 →
P30121	—	1.000	P30121 →
P48032	—	1.000	P48032 →
Q9TTY1	—	0.999	Q9TTY1 →
P25785	—	0.999	P25785 →
P16035	—	0.999	P16035 →
P16368	—	0.997	P16368 →
P26652	—	0.997	P26652 →
Q9TRZ7	—	0.996	Q9TRZ7 →
Q60453	—	0.995	Q60453 →
O73746	—	0.995	O73746 →
Q9WUC6	—	0.993	Q9WUC6 →
Q9VH14	—	0.993	Q9VH14 →
O97590	—	0.992	O97590 →
P30120	—	0.989	P30120 →
P12032	—	0.988	P12032 →
O42146	—	0.988	O42146 →
Q21265	—	0.986	Q21265 →
O35312	—	0.985	O35312 →
Q8UWD9	—	0.984	Q8UWD9 →
P12656	—	0.984	P12656 →
B4F6N6	—	0.984	B4F6N6 →
O73798	—	0.983	O73798 →
O73824	—	0.982	O73824 →
Q8BH35	—	0.982	Q8BH35 →