Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.39 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6354585 | 0.72 | CYP1A2 (0.55) | CYP1A2MEN1KMT2AGABBR2GABBR1 | |
| Hydrochloric Acid SCHEMBL9340197 | 0.70 | LMNA (0.56) | CYP1A2MEN1KMT2AGABBR2GABBR1 | |
| SCHEMBL9336343 | 0.70 | CYP1A2 (0.42) | CYP1A2MEN1KMT2AGABBR2GABBR1 | |
| Hydrochloric Acid SCHEMBL9336334 | 0.69 | LMNA (0.42) | CYP1A2MEN1KMT2AGABBR2GABBR1 | |
| SCHEMBL2353070 | 0.66 | CYP1A2 (0.57) | CYP1A2MEN1KMT2AGABBR2GABBR1 | |
| SCHEMBL6351470 | 0.65 | CYP1A2 (0.52) | CYP1A2MEN1KMT2AGABBR2GABBR1 | |
| Hydrochloric Acid SCHEMBL9336348 | 0.64 | LMNA (0.52) | CYP1A2MEN1KMT2AGABBR2GABBR1 | |
| SCHEMBL6360421 | 0.62 | CYP1A2 (0.53) | CYP1A2MEN1KMT2AGABBR2GABBR1 | |
| SCHEMBL6353688 | 0.62 | LMNA (0.45) | CYP1A2MEN1KMT2AGABBR2GABBR1 | |
| Hydrochloric Acid SCHEMBL9336340 | 0.62 | LMNA (0.45) | CYP1A2MEN1KMT2AGABBR2GABBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0319479-A2 | Substituted propane-phosphinic acid compounds | CIBA-GEIGY AG (CH) | 1989-06-07 | — | — | EP | disclosed |
| EP-0319482-A2 | Novel substituted propane phosphinic acid compounds | CIBA-GEIGY AG (CH) | 1989-06-07 | — | — | EP | disclosed |