Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL27793478 | 1.00 | FFAR3 (0.50) | FFAR3LCKFYNCA1CA2 | |
| Bicarbonate SCHEMBL10180649 | 0.87 | FFAR3 (0.46) | FFAR3LCKFYNCA1CA2 | |
| Bicarbonate SCHEMBL20423710 | 0.87 | FFAR3 (0.46) | FFAR3LCKFYNCA1CA2 | |
| SCHEMBL726605 | 0.80 | — | — | |
| Bicarbonate SCHEMBL27146755 | 0.80 | — | — | |
| SCHEMBL727585 | 0.80 | — | — | |
| SCHEMBL13423857 | 0.80 | — | — | |
| Bicarbonate SCHEMBL10180366 | 0.78 | — | — | |
| Bicarbonate SCHEMBL20423841 | 0.78 | FFAR3 (0.46) | FFAR3LCKFYNCA1CA2 | |
| Bicarbonate SCHEMBL26092734 | 0.78 | FFAR3 (0.46) | FFAR3LCKFYNCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9240616-B2 | Solvent including 1,2-dialkyl-1,2-difluoroethylene carbonate for non-aqueous electrolytic solution of lithium secondary battery | DAIKIN INDUSTRIES, LTD. (JP) | 2016-01-19 | — | — | US | claimed |
| US-8349500-B2 | Solvent for dissolving electrolyte salt of lithium secondary battery | DAIKIN INDUSTRIES, LTD. (JP) | 2013-01-08 | — | — | US | claimed |
| US-20110008682-A1 | SOLVENT FOR NON-AQUEOUS ELECTROLYTIC SOLUTION OF LITHIUM SECONDARY BATTERY | DAIKIN INDUSTRIES, LTD. (JP) | 2011-01-13 | — | — | US | claimed |
| US-20100310943-A1 | SOLVENT FOR DISSOLVING ELECTROLYTE SALT OF LITHIUM SECONDARY BATTERY | DAIKIN INDUSTRIES, LTD. (JP) | 2010-12-09 | — | — | US | claimed |
| CN-101911371-A | Solvent for nonaqueous electrolyte solution of lithium secondary battery | DAIKIN IND LTD | 2010-12-08 | — | — | CN | claimed |
| CN-101874326-A | Solvent for dissolving electrolyte salt of lithium secondary battery | DAIKIN IND LTD | 2010-10-27 | — | — | CN | claimed |
| WO-2022047628-A1 | ELECTROLYTE SOLUTION, ELECTROCHEMICAL DEVICE AND ELECTRONIC DEVICE | 宁德新能源科技有限公司 | 2022-03-10 | — | — | WO | disclosed |
| CN-113273011-A | Electrolyte solution, electrochemical device, and electronic device | 宁德新能源科技有限公司 | 2021-08-17 | — | — | CN | disclosed |
| CN-101911371-B | The solvent for nonaqueous electrolyte solution of lithium secondary battery | 大金工业株式会社 | 2016-06-22 | — | — | CN | disclosed |
| US-9240616-B2 | Solvent including 1,2-dialkyl-1,2-difluoroethylene carbonate for non-aqueous electrolytic solution of lithium secondary battery | DAIKIN INDUSTRIES, LTD. (JP) | 2016-01-19 | — | — | US | disclosed |
| US-8349500-B2 | Solvent for dissolving electrolyte salt of lithium secondary battery | DAIKIN INDUSTRIES, LTD. (JP) | 2013-01-08 | — | — | US | disclosed |
| US-20110008682-A1 | SOLVENT FOR NON-AQUEOUS ELECTROLYTIC SOLUTION OF LITHIUM SECONDARY BATTERY | DAIKIN INDUSTRIES, LTD. (JP) | 2011-01-13 | — | — | US | disclosed |
| US-20100310943-A1 | SOLVENT FOR DISSOLVING ELECTROLYTE SALT OF LITHIUM SECONDARY BATTERY | DAIKIN INDUSTRIES, LTD. (JP) | 2010-12-09 | — | — | US | disclosed |
| CN-101911371-A | Solvent for nonaqueous electrolyte solution of lithium secondary battery | DAIKIN IND LTD | 2010-12-08 | — | — | CN | disclosed |
| CN-101874326-A | Solvent for dissolving electrolyte salt of lithium secondary battery | DAIKIN IND LTD | 2010-10-27 | — | — | CN | disclosed |