Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL20423710 | 0.83 | FFAR3 (0.46) | FFAR3LCKFYNCA1CA2 | |
| Bicarbonate SCHEMBL10180649 | 0.83 | FFAR3 (0.46) | FFAR3LCKFYNCA1CA2 | |
| SCHEMBL1828737 | 0.82 | — | — | |
| Tetrafluoroethylene SCHEMBL27662225 | 0.78 | LMNA (0.42) | FFAR3LCKFYNCA1CA2 | |
| Bicarbonate SCHEMBL27793478 | 0.78 | FFAR3 (0.50) | FFAR3LCKFYNCA1CA2 | |
| Tetrafluoroethylene SCHEMBL28004090 | 0.78 | FFAR3 (0.64) | FFAR3LCKFYNCA1CA2 | |
| Bicarbonate SCHEMBL1058643 | 0.78 | FFAR3 (0.50) | FFAR3LCKFYNCA1CA2 | |
| Tetrafluoroethylene SCHEMBL321363 | 0.77 | CA1 (0.56) | FFAR3LCKFYNCA1CA2 | |
| Bicarbonate SCHEMBL4832988 | 0.77 | FFAR3 (0.60) | FFAR3LCKFYNCA1CA2 | |
| Tetrafluoroethylene SCHEMBL28869053 | 0.77 | CA1 (0.56) | FFAR3LCKFYNCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113273011-A | Electrolyte solution, electrochemical device, and electronic device | 宁德新能源科技有限公司 | 2021-08-17 | — | — | CN | disclosed |
| US-11043699-B2 | Nonaqueous electrolyte solution and method for producing nonaqueous electrolyte secondary battery | TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) | 2021-06-22 | — | — | US | disclosed |
| US-20180219259-A1 | NONAQUEOUS ELECTROLYTE SOLUTION AND METHOD FOR PRODUCING NONAQUEOUS ELECTROLYTE SECONDARY BATTERY | TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) | 2018-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11043699-B2 | Nonaqueous electrolyte solution and method for producing nonaqueous electrolyte secondary battery | NAF1, CA2, CA1 | FFAR3 3077/4885LCK 3570/4885FYN 2540/4885 |
| US-20180219259-A1 | NONAQUEOUS ELECTROLYTE SOLUTION AND METHOD FOR PRODUCING NONAQUEOUS ELECTROLYTE SECONDARY BATTERY | NAF1, CA2, CA1 | FFAR3 3077/4885LCK 3570/4885FYN 2540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.