Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8578277 | 0.81 | MAOB (0.50) | KMT2AMEN1MAOB | |
| SCHEMBL6156845 | 0.81 | POLB (0.57) | NPC1RAB9AKMT2AMEN1CYP1A2 | |
| SCHEMBL6155050 | 0.81 | CA1 (0.50) | CA1CA2 | |
| SCHEMBL14952332 | 0.78 | CA1 (0.53) | CA1CA2NPC1RAB9ANOTUM | |
| SCHEMBL2776741 | 0.78 | CA1 (0.53) | CA1CA2NPC1RAB9ANOTUM | |
| SCHEMBL28564102 | 0.75 | NPC1 (0.65) | CA1CA2NPC1RAB9AKMT2A | |
| SCHEMBL12294594 | 0.75 | NPC1 (0.65) | CA1CA2NPC1RAB9AKMT2A | |
| SCHEMBL21066127 | 0.74 | NPC1 (0.49) | CA1CA2NPC1RAB9ANOTUM | |
| SCHEMBL3984065 | 0.74 | NPC1 (0.59) | CA1CA2NPC1RAB9AKMT2A | |
| SCHEMBL14880239 | 0.73 | MAOB (0.52) | CA1CA2NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313997-A2 | Medicine, therein contained phosphor containing 2-isoxazolidines and isoxazoles, as well as process for preparing those heterocyclic compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-05-03 | — | — | EP | disclosed |