Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10586602 | 0.81 | CA1 (0.53) | CA1CA2 | |
| SCHEMBL27832939 | 0.81 | MIF (0.54) | — | |
| SCHEMBL27619239 | 0.81 | LMNA (0.41) | CA1CA2 | |
| SCHEMBL6156845 | 0.81 | POLB (0.57) | ATM | |
| SCHEMBL6155053 | 0.76 | CA1 (0.50) | CA1CA2ATMPKM | |
| SCHEMBL11982233 | 0.76 | CA1 (0.54) | CA1CA2ATMPKM | |
| SCHEMBL10622110 | 0.76 | CA1 (0.46) | CA1CA2ATMPKM | |
| SCHEMBL6939090 | 0.74 | TSHR (0.51) | CA1CA2ATM | |
| SCHEMBL28653891 | 0.74 | CA1 (0.49) | CA1CA2ATMPKM | |
| SCHEMBL28005074 | 0.73 | CA1 (0.51) | CA1CA2ATMPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6933283-B2 | 11-deoxy azalide antibacterials | ABBOTT LABORATORIES (US) | 2005-08-23 | — | — | US | claimed |
| EP-1501847-A2 | 11-DEOXY AZALIDE ANTIBACTERIALS | Abbott Laboratories (US) | 2005-02-02 | — | — | EP | claimed |
| EP-1499326-A1 | OXOLIDE ANTIBACTERIALS | Abbott Laboratories (US) | 2005-01-26 | — | — | EP | claimed |
| US-20040014953-A1 | 11-Deoxy azalide antibacterials | ABBVIE INC. | 2004-01-22 | — | — | US | claimed |
| WO-2003090760-A1 | OXOLIDE ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2003-11-06 | — | — | WO | claimed |
| WO-2003090679-A2 | 11-DEOXY AZALIDE ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2003-11-06 | — | — | WO | claimed |
| EP-0313997-B1 | Medicine, therein contained phosphor containing 2-isoxazolidines and isoxazoles, as well as process for preparing those heterocyclic compounds | HOECHST AG (DE) | 1994-03-09 | — | — | EP | claimed |
| US-6933283-B2 | 11-deoxy azalide antibacterials | ABBOTT LABORATORIES (US) | 2005-08-23 | — | — | US | disclosed |
| EP-1501847-A2 | 11-DEOXY AZALIDE ANTIBACTERIALS | Abbott Laboratories (US) | 2005-02-02 | — | — | EP | disclosed |
| EP-1499326-A1 | OXOLIDE ANTIBACTERIALS | Abbott Laboratories (US) | 2005-01-26 | — | — | EP | disclosed |
| US-20040014953-A1 | 11-Deoxy azalide antibacterials | ABBVIE INC. | 2004-01-22 | — | — | US | disclosed |
| WO-2003090679-A2 | 11-DEOXY AZALIDE ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2003-11-06 | — | — | WO | disclosed |
| WO-2003090760-A1 | OXOLIDE ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2003-11-06 | — | — | WO | disclosed |
| EP-0313997-A2 | Medicine, therein contained phosphor containing 2-isoxazolidines and isoxazoles, as well as process for preparing those heterocyclic compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-05-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014953-A1 | 11-Deoxy azalide antibacterials | TOP1, TOP2B, TOP2A | CA1 3536/4885CA2 4255/4885ATM 4431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.