Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15391806 | 0.83 | ALDH1A1 (0.46) | ALDH1A1ADRA2BPTGS1TDP1KDM4E | |
| SCHEMBL2091208 | 0.83 | ALDH1A1 (0.46) | ALDH1A1ADRA2BPTGS1TDP1KDM4E | |
| SCHEMBL2493370 | 0.82 | ALDH1A1 (0.45) | ALDH1A1ADRA2BPTGS1TDP1KDM4E | |
| SCHEMBL112134 | 0.79 | ALDH1A1 (0.50) | ALDH1A1ADRA2BPTGS1TDP1KDM4E | |
| SCHEMBL29893374 | 0.79 | ALDH1A1 (0.50) | ALDH1A1ADRA2BPTGS1TDP1KDM4E | |
| SCHEMBL8618190 | 0.77 | ALDH1A1 (0.41) | ALDH1A1ADRA2BPTGS1TDP1KDM4E | |
| Hydrochloric Acid SCHEMBL4379610 | 0.77 | ALDH1A1 (0.48) | ALDH1A1ADRA2BPTGS1TDP1KDM4E | |
| Hydrochloric Acid SCHEMBL27585317 | 0.77 | ALDH1A1 (0.48) | ALDH1A1ADRA2BPTGS1TDP1KDM4E | |
| Aniline SCHEMBL22169117 | 0.76 | TSHR (0.44) | ALDH1A1ADRA2BPTGS1TDP1KDM4E | |
| SCHEMBL29201487 | 0.75 | ALDH1A1 (0.46) | ALDH1A1ADRA2BPTGS1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318782-A2 | Substituted benzoyl(thio) ureas | BAYER AG (DE) | 1989-06-07 | — | — | EP | disclosed |