SCHEMBL10587148

SCHEMBL10587148

NC(=O)/C=C/C(N)=O.O=C1CC2(CC2)C(=O)OCCO1

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.37
CYP2C9 P11712 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2074641 0.84 LMNA (0.43) LMNACYP2C9
Ethylene Glycol SCHEMBL1242163 0.79 LMNA (0.41) LMNACYP2C9
SCHEMBL8855100 0.66 LMNA (0.43) LMNACYP2C9
SCHEMBL251860 0.64 LMNA (0.48) LMNACYP2C9
SCHEMBL1396017 0.63 CA1 (0.48) LMNACYP2C9
SCHEMBL8603859 0.62
Ethylene Glycol SCHEMBL588031 0.61 CA1 (0.41) LMNACYP2C9
SCHEMBL5860687 0.61 LMNA (0.55) LMNACYP2C9
SCHEMBL11366827 0.61 CA1 (0.50) LMNA
SCHEMBL8047024 0.61 CA1 (0.50) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4835248-A Biologically degradable polyamide for depot preparations having controlled release of the active compound HOECHST AKTIENGESELLSCHAFT (DE) 1989-05-30 US disclosed