Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KDM5A | P29375 | 3/20 | 0.43 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10588198 | 0.98 | CYP1A2 (0.48) | CYP1A2HPGDKDM5APHF8KDM2A | |
| SCHEMBL10586989 | 0.98 | CYP1A2 (0.48) | CYP1A2HPGDKDM5APHF8KDM2A | |
| SCHEMBL7950485 | 0.98 | CYP1A2 (0.48) | CYP1A2HPGDKDM5APHF8KDM2A | |
| SCHEMBL10587895 | 0.95 | KDM5A (0.40) | CYP1A2HPGDKDM5APHF8KDM2A | |
| SCHEMBL7863957 | 0.91 | KDM5A (0.53) | CYP1A2HPGDKDM5APHF8KDM2A | |
| SCHEMBL10587786 | 0.90 | — | — | |
| SCHEMBL1412080 | 0.85 | HPGD (0.52) | HPGDEPHX1TP53NPC1RAB9A | |
| SCHEMBL7028763 | 0.83 | HPGD (0.55) | CYP1A2HPGDEPHX1TP53NPC1 | |
| SCHEMBL10586034 | 0.83 | HPGD (0.55) | CYP1A2HPGDEPHX1TP53NPC1 | |
| SCHEMBL10586022 | 0.83 | HPGD (0.55) | CYP1A2HPGDEPHX1TP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0319316-A2 | Griseolic acid monoesters, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1989-06-07 | — | — | EP | disclosed |