SCHEMBL7863957

SCHEMBL7863957

[O]C(=O)CCCCCCCCCC1CCCC1

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM5A P29375 4/20 0.53
PHF8 Q9UPP1 4/20 0.53
KDM2A Q9Y2K7 4/20 0.53
KDM4C Q9H3R0 3/20 0.53
KDM4A O75164 1/20 0.51
SIGMAR1 Q99720 3/20 0.48
NAAA Q02083 2/20 0.47
MEN1 O00255 1/20 0.45
USP2 O75604 1/20 0.45
CYP3A4 P08684 1/20 0.45
ALOX15 P16050 1/20 0.45
KMT2A Q03164 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
KDM7A Q6ZMT4 1/20 0.43
EPHX1 P07099 1/20 0.42
CYP1A2 P05177 1/20 0.41
HPGD P15428 1/20 0.41
GLA P06280 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10587334 0.91 CYP1A2 (0.44) KDM5APHF8KDM2AKDM4CKDM4A
SCHEMBL10588198 0.89 CYP1A2 (0.48) KDM5APHF8KDM2AKDM4CKDM4A
SCHEMBL10586989 0.89 CYP1A2 (0.48) KDM5APHF8KDM2AKDM4CKDM4A
SCHEMBL7950485 0.89 CYP1A2 (0.48) KDM5APHF8KDM2AKDM4CKDM4A
SCHEMBL10587895 0.86 KDM5A (0.40) KDM5APHF8KDM2AKDM4CKDM4A
SCHEMBL2703035 0.84 KDM5A (0.54) KDM5APHF8KDM2AKDM4CKDM4A
SCHEMBL24095875 0.83 SIGMAR1 (0.54) KDM5APHF8KDM2AKDM4CKDM4A
SCHEMBL8627116 0.83 KDM5A (0.67) KDM5APHF8KDM2AKDM4CKDM4A
SCHEMBL1457154 0.83 KDM5A (0.67) KDM5APHF8KDM2AKDM4CKDM4A
SCHEMBL14890569 0.83 KDM5A (0.67) KDM5APHF8KDM2AKDM4CKDM4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0623608-B1 BENZOPYRAN DERIVATIVE, PRODUCTION THEREOF, AND PHARMACEUTICAL PREPARATION CONTAINING THE SAME AS ACTIVE INGREDIENT TEIJIN LTD (JP) 2001-05-30 EP disclosed
EP-0623608-A1 BENZOPYRAN DERIVATIVE, PRODUCTION THEREOF, AND PHARMACEUTICAL PREPARATION CONTAINING THE SAME AS ACTIVE INGREDIENT TEIJIN LIMITED (JP) 1994-11-09 EP disclosed