Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 9/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HRH2 | P25021 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 3/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602838 | 0.95 | TLR7 (0.45) | NPC1RAB9ATLR7PDE4DLMNA | |
| SCHEMBL10587197 | 0.95 | TLR7 (0.45) | NPC1RAB9ATLR7PDE4DLMNA | |
| Propionic Acid SCHEMBL6724139 | 0.93 | NPC1 (0.46) | NPC1RAB9ATLR7PDE4DLMNA | |
| SCHEMBL8126603 | 0.87 | TLR7 (0.47) | NPC1RAB9ATLR7PDE4DLMNA | |
| SCHEMBL10732746 | 0.86 | TLR7 (0.51) | NPC1RAB9ATLR7PDE4DLMNA | |
| SCHEMBL8125691 | 0.86 | TLR7 (0.46) | TLR7PDE4DLMNAPOLBHRH2 | |
| SCHEMBL3185729 | 0.84 | TLR7 (0.67) | NPC1RAB9ATLR7PDE4DLMNA | |
| SCHEMBL9602030 | 0.84 | TLR7 (0.47) | TLR7PDE4DLMNAPOLBHRH2 | |
| Hydrochloric Acid SCHEMBL6925023 | 0.83 | HTR4 (0.48) | HTR2AHTR2BKCNH2 | |
| Acetic Acid SCHEMBL8326365 | 0.83 | TLR7 (0.46) | NPC1RAB9ATLR7PDE4DLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0310950-A1 | Quinoline intermediates for the synthesis of 1H-imidazo[4,5-c]quinolines and 1H-imidazo[4,5-c]quinolin-4-amimes | RIKER LABORATORIES, INC. (US) | 1989-04-12 | — | — | EP | disclosed |
| US-4698348-A | 1H-imidazo[4,5-c]quinolines and their use as bronchodilating agents | RIKER LABORATORIES, INC. (US) | 1987-10-06 | — | — | US | disclosed |
| US-4689338-A | 1H-Imidazo[4,5-c]quinolin-4-amines and antiviral use | RIKER LABORATORIES, INC. (US) | 1987-08-25 | — | — | US | disclosed |