Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 5/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10584290 | 0.87 | ALDH1A1 (0.44) | TRPV1STSKCNA5EDNRA | |
| SCHEMBL10589397 | 0.87 | APP (0.44) | TRPV1KCNA5 | |
| SCHEMBL10589903 | 0.86 | PSEN1 (0.46) | HTR1AHTR7TRPV1STSKCNA5 | |
| SCHEMBL10583842 | 0.81 | FFAR4 (0.56) | TRPV1KCNA5 | |
| SCHEMBL10594694 | 0.80 | GAA (0.42) | ABCC9PGRSIRT2SIRT1HTR1A | |
| SCHEMBL10589777 | 0.80 | APP (0.44) | HTR1AHTR7TRPV1KCNA5 | |
| SCHEMBL10584603 | 0.79 | KCNA5 (0.40) | TRPV1STSKCNA5 | |
| SCHEMBL10587463 | 0.78 | KCNA5 (0.52) | TRPV1KCNA5 | |
| SCHEMBL10584607 | 0.78 | STS (0.45) | TRPV1STSKCNA5 | |
| SCHEMBL6559509 | 0.75 | TRPV1 (0.45) | TRPV1KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0315009-A2 | Chroman derivatives, process for their preparation and their use in medicines | BAYER AG (DE) | 1989-05-10 | — | — | EP | disclosed |